J Korean Ophthalmol Soc > Volume 53(7); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(7):1002-1010.
DOI: https://doi.org/10.3341/jkos.2012.53.7.1002    Published online July 15, 2012.
Correlation Between Central Corneal Thickness and Glaucomatous Damage.
Yoon Jeon Kim, Jung Hwa Na, Youngrok Lee, Kyung Rim Sung
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sungeye@gmail.com
중심각막두께와 녹내장성 손상의 상관관계에 대한 연구
김윤전⋅나정화⋅이영록⋅성경림
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Abstract
PURPOSE
To evaluate the correlations between central corneal thickness (CCT) and optic disc and retinal nerve fiber layer (RNFL) parameters determined by spectral domain optical coherence tomography (SD OCT) and visual field (VF) global indices. METHODS: The present study included 151 eyes diagnosed with open-angle glaucoma (OAG) and 135 glaucoma suspect (GS) eyes. The CCT, RNFL thickness, optic disc parameters, and VF global indices were measured. The relationships between CCT and RNFL thickness, optic disc parameters, and VF global indices were assessed by linear regression analysis. RESULTS: Intraocular pressure (IOP, p < 0.001) and VF mean deviation (p = 0.005) in all participants, age (p = 0.017) and IOP (p = 0.003) in the GS group, and IOP (p = 0.002) and inferior RNFL thickness (p = 0.017) in the OAG group were significantly associated with CCT. Among the optic disc parameters, rim area, average cup/disc ratio, and vertical cup/disc ratio were significantly associated with CCT in all participants in the univariate but not multivariate analysis. CONCLUSIONS: Optic disc parameters obtained by SD OCT were not correlated with CCT in the OAG or GS group, while RNFL thickness and VF mean deviation showed associations.
Key Words: Central corneal thickness;Optic disc parameters;Retinal nerve fiber layer thickness;Spectral domain optical coherence tomography;Visual field indices


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