Journal of the Korean Ophthalmological Society 2006;47(7):1043-1048.
Published online July 31, 2006.
Clinical Outcomes 10 Years after Penetrating Keratoplasty.
Seung Jae Lee, Eun Young Cho, Man Soo Kim
Department of Ophthalmology, Kangnam St. mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. mskim@catholic.ac.kr
전층각막이식수술 후 10년 경과 관찰
이승재,조은영,김만수
Department of Ophthalmology, Kangnam St. mary`s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence:  Seung Jae Lee, M.D.
Abstract
PURPOSE
To evaluate clinical outcomes 10 years after penetrating keratoplasty. METHODS: We analyzed 69 eyes of 68 patients who had undergone penetrating keratoplasty by one surgeon between 1994 and 1995. We evaluated long-term outcome of corneal graft and follow-up rates for 10 years after surgery. Slitlamp biomicroscopy was performed to assess the condition of grafts. Visual acuity, manifest refraction, central corneal thickness, and endothelial cell count were measured if the patient visited the clinic. The patients who did not visit the clinic were asked to subjectively assess visual acuity and gross corneal clarity to gauge the condition of the graft cornea by telephone survey. RESULTS: The mean age was 42.5 years and the sex distribution of recipients was predominantly male (M:F=48:20). At 10 years after surgery, 28 grafts were clear, 28 grafts were known to have failed, and the status of 13 grafts remained unknown. The highest survival rate was noted in keratoconus, and the major preoperative diseases of graft failure were bullous keratopathy and infectious keratitis. Fifty percent of patients attended all follow-up visits over the 10 years. CONCLUSIONS: The graft survival rate at 10 years after keratoplasty was 50%.
Key Words: Graft rejection;Graft survival;Penetrating keratoplasty


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