| A Case of Phoma glomerata Keratitis Occurred in Recurrent Herpes Simplex Keratitis Cicatrix. |
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Jong Hwa Jun, Nam Hee Ryoo, Sung Dong Chang |
1Department of Ophthalmology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea. changsd@dsmc.or.kr
2Department of Laboratory Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea. |
| 반복된 단순포진 각막염의 반흔에 발생한 포마 그로메라타 진균각막염 1예 |
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전종화1⋅류남희2⋅장성동1 |
Department of Ophthalmology, Dongsan Medical Center, Keimyung University School of Medicine1, Daegu, Korea
Department of Laboratory Medicine, Dongsan Medical Center, Keimyung University School of Medicine2, Daegu, Korea |
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| Abstract |
PURPOSE
To report a case of Phoma glomerata keratitis occurring in recurrent herpes simplex keratitis cicatrix. CASE SUMMARY: A 63-year-old male patient was admitted to our hospital with complaints of abrupt visual deterioration and ocular pain in his left eye. He was treated for recurrent herpes simplex keratitis in the same eye 12 years prior. Because central desmatocele was observed as a result of advanced corneal stromal melting, Gram staining, Potassium Hydroxide (KOH) mount, and culture were performed in corneal scrape specimens. On microbiological evaluation, a Phoma species was detected and Phoma glomerata was diagnosed using DNA sequencing method. Two consecutive amniotic membrane transplantations were performed with topical antifungal agents. The lesion was not improved when using topical amphotericin B and natamycin eyedrops, thus fluconazole eyedrops were used additionally. The corneal infection was resolved with central thick opacification. CONCLUSIONS: In the present case, herpetic keratitis was the main underlying causative factor because the patient had no past history of trauma. When diverse appearances of keratitis occur in herpes simplex keratitis patients, clinicians need to consider the concurrence of fungal infection, especially Phoma glomerata, a rare fungal organism. |
| Key Words:
Cicatrix;Herpes simplex;Keratitis;Phoma glomerata;Recurrent |
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