Three Cases of Secondary Fungal Infection in Herpes Simplex Keratitis.

Mun, Gui Hyeong; Park, Yeoung Geol; You, In Cheon; Yoon, Kyung Chul

doi:2010.51.9.1271

J Korean Ophthalmol Soc > Volume 51(9); 2010 > Article

Case Report

Journal of the Korean Ophthalmological Society 2010;51(9):1271-1275.
DOI: https://doi.org/10.3341/jkos.2010.51.9.1271 Published online September 15, 2010.

Three Cases of Secondary Fungal Infection in Herpes Simplex Keratitis.

Gui Hyeong Mun, Yeoung Geol Park, In Cheon You, Kyung Chul Yoon

¹Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. kcyoon@chonnam.ac.kr
²Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea.

단순포진각막염 환자에서 발생한 진균각막염 3예

문귀형¹ㆍ박영걸¹ㆍ유인천²ㆍ윤경철¹

Department of Ophthalmology, Chonnam National University Medical School¹, Gwangju, Korea Department of Ophthalmology, Chonbuk National University Medical School², Jeonju, Korea

Abstract

PURPOSE
To report several cases of secondary infection by fungus in herpes simplex keratitis. CASE SUMMARY: A retrospective chart review was performed on 3 eyes of 3 patients who were without improvement and diagnosed with fungal keratitis by smear and culture on prior presentation with herpetic keratitis. Two cases were diagnosed with fungal keratitis, based on the results of culture. Fungal keratitis by Candida albicans was improved with antifungal agents, but a case caused by Fusarium species was more aggravated, regardless of antifungal agents. One case was improved by antifungal medications, which was diagnosed with fungal keratitis by the fungal hyphae manifestation on KOH preparation. CONCLUSIONS: Secondary microbial infection should be considered, when the lesion had no improvement with antiviral agents in herpetic keratitis.

Key Words: Fungus;Herpetic keratitis;Secondary infection