| Glaucoma Diagnostic Performance of Macular and Retinal Nerve Fiber Layer by Spectral-Domain Optical Coherence Tomography. |
|
Youngrok Lee, Kyung Rim Sung, Jung Taeck Hong, Jung Hwa Na |
|
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sungeye@gmail.com |
| 녹내장 진단에서 스펙트럼 영역 빛간섭단층촬영기로 측정한 황반과 망막신경섬유층 두께의 유용성 |
|
이영록ㆍ성경림ㆍ홍정택ㆍ나정화 |
|
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea |
|
|
| Abstract |
PURPOSE
To compare the performance of glaucoma diagnosis according to the macular and peripapillary retinal nerve fiber layer (RNFL) thicknesses, as determined by spectral domain optical coherence tomography (OCT). METHODS: Ninety-six normal, 63 early glaucoma and 37 moderate to advanced glaucomatous eyes were imaged by Cirrus OCT. The areas under the receiver operating characteristics curves (AUCs) of macular and RNFL thicknesses were calculated for discrimination of normal and glaucomatous eyes. The sensitivity and specificity of normative classification of each parameter were assessed. RESULTS: The glaucoma diagnostic capability determined by AUC was greater when based on the peripapillary RNFL than the macular thickness (0.914, 0.775, p<0.001). Both the early and the moderate-to-advanced group showed higher AUCs in peripapillary RNFL thickness (early glaucoma group; 0.870, 0.670, p<0.001, moderate to advanced glaucoma group; 0.990, 0.954, p=0.03). The inferior outer sector of macular thickness showed highest sensitivity among the parameters (58%). CONCLUSIONS: Although Cirrus OCT applied to determine macular thickness did not outperform that applied to determine peripapillary RNFL thickness in glaucoma diagnosis, applying Cirrus OCT to determine both thicknesses in diagnosis may help in understanding a patient's status. |
| Key Words:
Cirrus spectral domain Optical coherence tomography;Glaucoma;Macular thickness;Peripapillary retinal nerve fiber layer thickness |
|
PDF Links
Full text via DOI
Download Citation
