Journal of the Korean Ophthalmological Society 1970;11(4):49-54.
Published online April 1, 1970.
Mydriatic Action of Phenylephrine Hydrochloride.
Kun Soo Hong
Department of Ophthalmology, Woo Sok University Medical College, Seoul, Korea.
Phenylephrine 산동에 (散瞳) 대한 (對) 검토 (檢討)
김정환(Jung Whan Kim),홍건수(Kun Soo Hong)
Abstract
Phenylephrine hydrochloride has been widely used in ocular theraphy and examination, such as the treatment of uveitis and glaucoma and examination of the eye ground. In this study, mydriatic action of single instillation of 10% phenylephrine hydrochloride solution was compared with that of combined instillation of 10% phenylephrine hydrochloride solution and 0.5% tetracaine drops in 110 brown eyes. The following results were obtained; 1) In 55 eyes, the diameter of the pupil reached more than 7 mm about 45 minutes after instillation of 10% phenylephrine hydrochloride solution. 2) In case of combined instillation of 0.5% tetracaine solution and 10% phenylephrine hydrochloride solution, the onset of mydriasis was delayed. 3) In the case of combined instillation of 0.5% tetracaine and 10% phenylephrine hydrochloride solution with 5 and 10 minutes interval, the action of mydriasis was acceralated. 4) After tonometry, the action of mydriasis was more acceralated.


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