| Clinical Evaluation of Recurrence Rate of Pterygium Operation according to Mitomycin C Concentration. |
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Sang Un Oh, Won Woo Kim, Hwang Ki Kim |
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Department of Ophthalmology, Kim'sEye Hospital, Seoul, Korea. phaco@unitel.co.kr |
| 원발성 군날개 수술에서 Mitomycin C 점안액의 농도에 따른 재발률에 관한 고찰 |
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오상언 ( Sang Un Oh ) , 김원우 ( Won Woo Kim ) , 김황기 ( Hwang Ki Kim ) |
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| Abstract |
PURPOSE
The authors compared the recurrence rate and complications of primary pterygium operation with respect to mitomycin C concentration. METHODS: Four hundred twenty three eyes with primary pterygium underwent surgery using the bared sclera method. One hundred nineteen eyes randomly chosen were treated with 0.02% mitomycin C (Group I) twice a day for 5days, 138 eyes were treated with 0.01% mitomycin C (Group II), and 166 eyes were treated with 0.005% mitomycin C (Group III). RESULTS: During the mean follow-up period of 6 months, the overall recurrence rate was 14.7% (62 eyes). Recurrence rates in each group : 8.4% (10 eyes) in Group I , 13.7% (19 eyes) in Group II , and 19.9% (33eyes) in Group III . Complications seen in Group I were corneal abrasion (1 eye), symblepharon (1 eye), and postoperative corneal scar (1 eye). Complications seen in Group II were symblepharon (1 eye), and postoperative corneal opacity (2 eye) and seen in Group III were symblepharon (1 eye), and postoperative corneal opacity (1 eye). We conclude that a higher concentration of mitomycin C (0.2 mg/ml) reduces the recurrence rate of pterygium. CONCLUSIONS: We recommend the use of mitomycin C concentration of 0.02% twice a day for 5days to lower the recurrence rate and complications after excision of primary pterygium |
| Key Words:
Mitomycin C;Primary pterygium;Recurrence rate |
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