Postnatal Risk Factors of Retinopathy of Prematurity.

Kim, Tae Im; Sohn, Jun Hong; Yoon, Young Hee; Kim, Ki Soo; Pi, Soo Young

Original Article

Journal of the Korean Ophthalmological Society 2000;41(5):1229-1235.
Published online May 1, 2000.

Postnatal Risk Factors of Retinopathy of Prematurity.

Tae Im Kim, Jun Hong Sohn, Young Hee Yoon, Ki Soo Kim, Soo Young Pi

¹Department of Ophthalmology, Asan Medical Center, College of Medicine, University of Ulsan, Korea.
²Department of Pediatrics, University of Ulsan, College of Medicine, Seoul, Korea.

미숙아망막병증의 출생 후 위험인자

김태임(Tae Im Kim),손준홍(Jun Hong Sohn),윤영희(Young Hee Yoon),김기수(Ki Soo Kim),피수영(Soo Young Pi)

Abstract

In order to investigate the risk factors of retinopathy of prematurity[ROP], we retropspectively reviewed the medical records of 425 premature babies who had been admitted in our neonate intensive care unit between January 1994 and December 1998.After excluding 33 babies who had serious congenital anomalies, 83 out of 392 babies[20.7%]developed various stages of ROP.Gestational age and birthweight were the most significant risk factors. Among postnatal factors use of ventilator for 48 hours orlonger, apnea, and use of surfactant were independently increasing the progression of ROP in a linear logistic regression analysis.Other factors such as history of transfusion and sepsis had a tendency to worsen the retinopathy.On the other hand, fluctuation in blood gas, low apgar score or anemia did not seem to effect the progression of retinopathy. In conclusion, careful monitoring would be warrented when the premature babies had additional risk factors as listed above.

Key Words: Retionpathy of prematurity;Postnatal risk factors;Gestational age;Birth weight