J Korean Ophthalmol Soc > Volume 60(10); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(10):953-958.
DOI: https://doi.org/10.3341/jkos.2019.60.10.953    Published online October 15, 2019.
Risk Factors that Affects Progression of Type 2 Retinopathy of Prematurity.
Ga Hee Han, Ji Woong Chang
1Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. naizzima@hanmail.net
2Graduate Program in Cognitive Science, Yonsei University, Seoul, Korea.
2형 미숙아망막병증의 발생 후 진행에 관련된 위험인자 분석
한가희1,2 · 장지웅1,2
인제대학교 의과대학 일산백병원 안과학교실1, 연세대학교 인지과학협동과정2
Correspondence:  Ji Woong Chang,
Email: naizzima@hanmail.net
Received: 4 April 2019   • Revised: 4 May 2019   • Accepted: 24 September 2019
Abstract
PURPOSE
To identify risk factors that affect the development of type 2 retinopathy of prematurity (ROP) and progression to type 1 or threshold ROP requiring treatment. METHODS: The medical records of premature infants born with a birth weight ≤1,500 g or a gestational age ≤32 weeks were retrospectively reviewed. Potential risk factors were divided into systemic and ophthalmic factors and analyzed by univariate and multivariate logistic regression analyses. RESULTS: Three hundred and twenty-four eyes met the screening criteria. Among them, 41 eyes (12.65%) progressed to type 2 ROP and 21 eyes (6.48%) received treatment after progression to type 1 or threshold ROP. The systemic risk factor associated with progression from type 2 ROP was periventricular leukomalacia and the ophthalmic factor was the existence of nasal ROP at the time of diagnosis of type 2 ROP. CONCLUSIONS: Careful examination was needed when type 2 ROP with periventricular leukomalacia or nasal ROP developed because there was a high probability of progression and treatment.
Key Words: Retinopathy of prematurity;Risk factors;Type 2 retinopathy of prematurity


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