The Effect of Intraocular 1% Lidocaine on the Corneal Endothelium during Phacoemulsification.

Yoon, Sang Won; Chung, Young Taek

Original Article

Journal of the Korean Ophthalmological Society 1999;40(5):1223-1227.
Published online May 1, 1999.

The Effect of Intraocular 1% Lidocaine on the Corneal Endothelium during Phacoemulsification.

Sang Won Yoon, Young Taek Chung

Department of Ophthalmology, College of Medicine, Chonbuk National University.

수정체유화술시 전방에 이용되는 1% Lidocaine이 각막내피세포에 미치는 영향

윤상원(Sang Won Yoon),정영택(Young Taek Chung)

Abstract

The aim of this study was to evaluate the influence of intraocular 1% lidocaine as an adjunct to topical anesthesia on corneal endothelial cell during phacoemulcification. We evaluated 38 patients(50 eyes). All patients underwent phacoemulsification and PCL implantaion. Twenty five eyes were used intraocular 1% lidocaine and topical anesthesia and others used only topical anesthesia. Endothelial cell density was examind preoperatively, and at 1 day, 1 week, 1 and 2 months postoperatively by specular microscopy. The difference of preoperative endothelial cell density between two groups was not statistically significant. In lidocaine-used group, the average endothelial cell loss was 7. 6%, 9. 2%, 10.4%, 10.6%at 1 day, 1 week, 1 and 2 months. In non used group, the average endothelial cell loss was 7. 4%, 9. 4%, 9. 9%, 11. 7%at 1 day, 1 week, 1 and 2 months. The difference of postoperative endothelial cell density between two groups was not statistically significant(P>0.1). From these results, we conclude that the intraocular lidocaine infusion for anesthesia had little effect on the corneal endothelial cell loss.

Key Words: Corneal endothelial cell;1% Lidocaine;Specular microscopy