| Corneal wound Healing Following Excimer Laser Photorefractive Keratectomy Using Pressure Patch, T-lens and Collagen Shield on Rabbit Cornea. |
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Hung Won Tchah, Jouug Koo Lee |
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Department of Ophthalmology, College of Medicine, University of Uisan, Asan Medical Center, Seoul, Korea. |
| 가토를 이용한 엑시머 수술후 각막상피 창상 치료와 조직학적 비교 |
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차흥원(Hung Won Tchah),이정규(Joung Koo Lee) |
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| Abstract |
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We studied the healing course and histologic change of ablated rabbit cornea following excimer laser photorefractive keratectomy using three different corneal wound healing methods; pressure patch, T-lens, collagen shield. Nine rabbits(18 eyes) were divided into three different groups according to its treatment method. Corneal status including the corneal haze, conjunctival injection, discharge amount at postoperative 1st day, 2nd day and 3rd day were the same, irrespective to the treatment method and corneal wound healing rate show no significant differentces in all the groups. The histologic feature revealed irregular epithelial hyperplasia and keratacyte infiltration in the superficial stromal layer on postoperative 3rd day and 7th day. These reactions lessened at postoperative 1 month. The cornea treated with pressure patch group revealed more severe tissue reaction when compared with the other groups, T-lens and collagen shield. These results suggest that the corneal wounds produced by excimer laser can be managed by T-lens as an another alternative method of wound treatment. |
| Key Words:
Collagen shield;Corneal wound healing;Excimer laser photorefractive keratectomy;Pressure patch;T-lens |
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