| Lid Wiper Epitheliopathy in Patients with Dry Eye Refractory to Conventional Medical Treatment. |
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Jungah Huh, In Ho Woo, Youngsub Eom, Su Yeon Kang, Hyo Myung Kim, Jong Suk Song |
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Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. crisim123@korea.ac.kr |
| 약물 치료에 반응이 없는 안구건조증 환자의 눈꺼풀경계부상피병변 평가 |
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허정아⋅우인호⋅엄영섭⋅강수연⋅김효명⋅송종석 |
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고려대학교 의과대학 안과학교실 |
Correspondence:
Jong-Suk Song
Email: crisim123@korea.ac.kr |
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Received: 8 March 2018 • Revised: 17 May 2018 • Accepted: 20 July 2018 |
| Abstract |
PURPOSE
We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment. METHODS: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol. RESULTS: The mean OSDI score was 48.06 ± 21.19; 34 patients (73.9%) were had scores ≥33. Lid wiper epitheliopathy was evident in 41 (89.1%), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 ± 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = −0.16, p = 0.279; r = 0.16, p = 0.298, respectively). CONCLUSIONS: Lid wiper epitheliopathy was present in about 90% of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score. |
| Key Words:
Correlation;Dry eye;Lid wiper epitheliopathy;Medical;Refractory |
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