J Korean Ophthalmol Soc > Volume 59(8); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(8):724-729.
DOI: https://doi.org/10.3341/jkos.2018.59.8.724    Published online August 15, 2018.
Anti-pseudomonal Effect of a Nephrite-containing Contact Lens Storage Case.
Sang Min Lee, Jae Woo Jung, Dong Hyun Lee, Sung Hee Park, Jong Heon Lee, Hak Sun Yu, Yoon Kyung Kim, Ji Eun Lee
1Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea. jiel75@hanmail.net
2Department of Parasitology and Tropical Medicine, Pusan National University School of Medicine, Yangsan, Korea.
3Department of Optometry, Busan Women's College, Busan, Korea.
4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
연옥이 첨가된 콘택트렌즈 보관용기의 항녹농균 효과
부산대학교 의학전문대학원 양산부산대학교병원 안과학교실1, 부산대학교 의학전문대학원 기생충학 및 열대의학교실2, 부산여자대학교 안경광학과3, 부산대학교 의학전문대학원 양산부산대학교병원 의생명융합연구소4
Correspondence:  Ji-Eun Lee
Email: jiel75@hanmail.net
Received: 14 February 2018   • Revised: 20 May 2018   • Accepted: 20 July 2018
To compare the anti-pseudomonal effect of nephrite-containing contact lens (CL) storage cases with conventional CL storage cases. METHODS: The degree of proliferation and adhesion of Pseudomonas aeruginosa (P. aeruginosa) on 1st–3rd generation silicone hydrogel contact lenses (SHCLs) was compared by using both 5% nephrite-containing CL storage cases and conventional CL storage cases. The degree of adhesion of P. aeruginosa to the CL was also compared in 1% or 5% nephrite solution and multipurpose solution (MPS). RESULTS: Nephrite-containing CL storage cases showed a significant inhibitory effect on P. aeruginosa proliferation (p = 0.03) and significantly reduced the number of adherent P. aeruginosa on all 1st–3rd generation SHCLs compared with conventional CL storage cases (p = 0.02, p = 0.03, and p < 0.01, respectively). There was no significant anti-pseudomonal effect of 1% and 5% nephrite solutions compared with MPS. CONCLUSIONS: Nephrite may be the next generation substance that reduces infectious keratitis caused by P. aeruginosa when added to CL storage cases.
Key Words: Contact lens storage case;Infectious keratitis;Multipurpose solution;Nephrite;Pseudomonas aeruginosa

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