J Korean Ophthalmol Soc > Volume 59(9); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(9):876-880.
DOI: https://doi.org/10.3341/jkos.2018.59.9.876    Published online September 15, 2018.
Bilateral Frosted Branch Angiitis in Kikuchi-Fujimoto Disease.
Hun Min Kim, Young Je Choi, Seong Taeck Kim
1Department of Ophthalmology, Chosun University School of Medicine, Gwangju, Korea. s20age@hanmail.net
2Gangjin Medical Center, Sinan, Korea.
양안 언가지모양혈관염을 동반한 기구치-후지모토병 1예
김훈민1⋅최영제2⋅김성택1
조선대학교 의과대학 안과학교실1, 강진의료원2
Correspondence:  Seong Taeck Kim,
Email: s20age@hanmail.net
Received: 17 May 2018   • Revised: 22 June 2018   • Accepted: 28 August 2018
Abstract
PURPOSE
A case of frosted branch angiitis in Kikuchi-Fujimoto disease is reported. CASE SUMMARY: A 33-year-old male complained of a sudden decrease in visual acuity that developed in both eyes 5 days prior. He suffered from a headache, chills, myalgia, and flank pain 1 week before. The initial best-corrected visual acuity (BCVA) was 0.1 in the right eye and 0.2 in the left eye. On slit lamp examination, no inflammatory finding was observed in the anterior chamber and vitreous body of both eyes. On fundus examination, a diffuse vascular sheathing-like frosted branch was found in the retinal vessels, and retinal hemorrhage was observed. Fluorescein angiography showed staining and leakage of dye along the vascular sheathing. Serological findings were negative, showing no evidence of an autoimmune disease or viral infection. Neck ultrasonography revealed non-tender left cervical lymph node enlargement >1 cm in diameter. Ultrasound-guided fine needle aspiration cytology showed findings compatible with Kikuchi-Fujimoto disease, including necrotic changes and pronounced karyorrhexis, plus histiocyte and lymphocyte infiltration without neutrophils. We started systemic steroid therapy. One month after treatment, the BCVA of both eyes improved to 1.0. CONCLUSIONS: In patients with frosted branch angiitis, systemic disease such as Kikuchi-Fujimoto disease should be considered.
Key Words: Frosted branch angiitis;Kikuchi-Fujimoto disease;Necrotizing lymphadenitis


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