J Korean Ophthalmol Soc > Volume 59(10); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(10):989-994.
DOI: https://doi.org/10.3341/jkos.2018.59.10.989    Published online October 15, 2018.
A Case of Choroidal Osteoma with Subretinal Hemorrhage Improved by Intravitreal Bevacizumab and Aflibercept Injections.
Charm Kim, Kyung Seek Choi, Hae Jung Sun
Department of Ophthalmology, Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. sunhj99@schmc.ac.kr
유리체 내 베바시주맙 및 애플리버셉트 주사를 통해 호전된 망막하출혈을 동반한 맥락막골종 1예
김 참⋅최경식⋅선해정
순천향대학교 의과대학 서울병원 안과학교실
Correspondence:  Hae Jung Sun,
Email: sunhj99@schmc.ac.kr
Received: 7 June 2018   • Revised: 24 July 2018   • Accepted: 27 September 2018
To report a case of choroidal osteoma (CO) complicated by extensive subretinal hemorrhage treated with intravitreal bevacizumab and aflibercept injections. CASE SUMMARY: A 42-year-old female patient presented with decreased visual acuity and a temporal visual field defect in the left eye. The patient had a history of retinal hemorrhage in the left eye 3 years prior, which improved without any treatment. The patient's visual acuity had decreased to 0.6 at the initial visit. On fundus examination, orange-colored elevated lesions involving the superior peripapillary area with massive subretinal hemorrhage extending to the macular area were revealed. Optical coherence tomography, fluorescein angiography, and B-scan ultrasonography results indicated CO complicated by choroidal neovascularization (CNV). With multiple intravitreal injections of bevacizumab and aflibercept (bevacizumab ×1, aflibercept ×2), the patient's visual acuity improved and the CNV lesion was kept stable without recurrence as of the 1-year follow-up visit. CONCLUSIONS: Intravitreal bevacizumab and aflibercept injections can be helpful in the treatment of CO complicated by CNV, by improving visual acuity and the retinal anatomy.
Key Words: Aflibercept;Bevacizumab;Choroidal osteoma;Subretinal hemorrhage

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