Semi-automatic Measurement of Ocular Volume from Facial Computed Tomography and Correlation with Axial Length. |
Junkyu Chung, In Ki Park, Samjin Choi, Jae Ho Shin |
1Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea. pbloadsky@naver.com 2Department of Ophthalmology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Korea. 3Department of Bioengineering, Kyung Hee University School of Medicine, Seoul, Korea. |
얼굴 전산화단층촬영 사진을 이용한 안구용적측정치와 안축장과의 상관관계 |
정준규1⋅박인기2⋅최삼진3⋅신재호1 |
경희대학교 의학전문대학원 강동경희대학교병원 안과학교실1, 경희대학교 의학전문대학원 경희의료원 안과학교실2, 경희대학교 의과대학 의공학교실3 |
Correspondence:
Jae-Ho Shin Email: pbloadsky@naver.com |
Received: 7 June 2018 • Revised: 27 August 2018 • Accepted: 20 February 2019 |
Abstract |
PURPOSE To measure the ocular volume from facial computed tomography (CT) scans using a semi-automatic computer program, and to analyze possible correlations between the axial length and ocular volume using regression analysis. METHODS: Forty eyes from 20 facial CT scans were used to measure the ocular volumes. The cross-sectional ocular areas were calculated using a semi-automatic program based on MATLAB r2009a (MathWorks, Inc., Natick, MA, USA), and the ocular volumes were calculated from serial cross-sectional areas. The axial lengths were measured by A-scan ultrasound. Statistical analysis including regression analysis was used to determine possible correlations between the ocular volumes and axial lengths. RESULTS: The mean ocular volumes measured in males and females were 7.16 ± 1.80 cm3 and 7.24 ± 3.38 cm3, respectively. The mean axial lengths measured in males and females were 23.47 ± 0.69 mm and 23.23 ± 1.64 mm, respectively. There were positive correlations using Pearson's correlation coefficient and the partial correlation coefficient adjusted by axial length. Using regression analysis, the following statistically significant equation was derived: (ocular volume [cm3] = 0.0056558 × axial length3 [mm3] − 0.1798106 × axial length2 [mm2] + 32.9008570 [p < 0.001, R2 = 0.384]). CONCLUSIONS: The ocular volume measurement tool in this study was noninvasive and very useful, without special equipment. Accurate estimation of ocular volumes by a statistical equation was feasible, and these findings may be helpful in further study of various ocular diseases and in predicting preoperative and postoperative ocular volumes. |
Key Words:
Axial length;Facial computed tomography;Ocular volume;Volume measurements |
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