J Korean Ophthalmol Soc > Volume 60(5); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(5):407-413.
DOI: https://doi.org/10.3341/jkos.2019.60.5.407    Published online May 15, 2019.
Dry Eye Syndrome after Refractive Surgery: Comparative Outcomes of SMILE and LASIK.
Ho Gil Jung, Gi Hyun Bae, Joo Young Kwag, Joo Hyun, Jin Seok Choi, Kyu Hong Pak, Sung Kun Chung
1Department of Ophthalmology, SahmYook Medical Center, Seoul, Korea.
2Saevit Eye Hospital, Goyang, Korea. eyekun@gmail.com
스마일수술과 펨토초라식수술 후 안구건조증 지표의 단기 관찰
정호길1⋅배지현1⋅곽주영2⋅현 주2⋅최진석2⋅박규홍2⋅정성근2
삼육서울병원안과1, 새빛안과병원2
Correspondence:  Sung Kun Chung,
Email: eyekun@gmail.com
Received: 26 July 2018   • Revised: 28 September 2018   • Accepted: 23 April 2019
To determine possible differences in dry eye syndrome in relation to surgery methods, especially between small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), in Korean patients. METHODS: This study involved 20 patients (20 eyes) who were treated with SMILE surgery and 23 patients (23 eyes) who were treated with FS-LASIK. The Schirmer test, tear film breakup time (TBUT), corneal staining score (CSS), and measurement of changes in the lipid layer thicknesses at one week, and 1 and 3 months after surgery were performed. Possible correlations between indicators of dry eye syndrome were then analyzed. RESULTS: There was a significant time difference in some indices. The TBUT was 5.52 ± 1.50 s after one week for SMILE patients and 4.59 ± 2.50 s for FS-LASIK patients (p = 0.02). The CSS was 0.50 ± 0.51 after 1 week for SMILE patients and 1.14 ± 0.99 after 1 week for FS-LASIK patients (p = 0.04). The CSS was 0.50 ± 0.51 after 1 month for SMILE patients and 1.10 ± 0.93 after 1 month for FS-LASIK patients (p = 0.03). Three months later, the CSS was 0.39 ± 0.50 for SMILE patients and 0.94 ± 0.85 for FS-LASIK patients (p = 0.03). However, the Schirmer test did not show a significant difference postoperatively for SMILE and FS-LASIK patients at 1 week (p = 0.44), 1 month (p = 0.68), and 3 months (p = 0.23). Additionally, the thickness of the tear film lipid layer did not show a significant difference during the same periods (p = 0.36, p = 0.43, and p = 0.72, respectively). CONCLUSIONS: When compared with FS-LASIK surgery, SMILE surgery resulted in significantly improved test results in the TBUT and CSS for dry eye syndrome.
Key Words: Dry eye syndrome;Lipiview;keratomileusis;Laser in situ (LASIK);Small incision lenticule extraction (SMILE)

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