J Korean Ophthalmol Soc > Volume 61(2); 2020 > Article
Journal of the Korean Ophthalmological Society 2020;61(2):205-208.
DOI: https://doi.org/10.3341/jkos.2020.61.2.205    Published online February 15, 2020.
Epstein-Barr Virus-related Corneal Endotheliitis Accompanied with Secondary Glaucoma.
Yong Wun Cho, Hyun Ji Kang, Gyu Nam Kim, Hyun A Kim, In Young Chung, Seong Jae Kim
1Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea. maya12kim@naver.com
2Health Science Institute, Gyeongsang National University, Jinju, Korea.
이차 녹내장이 동반된 엡스타인-바 바이러스 각막내피염
조용운1 · 강현지1 · 김규남1 · 김현아1 · 정인영1,2 · 김성재1,2
경상대학교 의과대학 안과학교실1, 경상대학교 건강과학연구원2
Correspondence:  Seong Jae Kim,
Email: maya12kim@naver.com
Received: 22 May 2019   • Revised: 26 June 2019   • Accepted: 22 January 2020
Abstract
PURPOSE
To report a case of Epstein-Barr virus-related corneal endotheliitis accompanied by secondary glaucoma. CASE SUMMARY: A 73-year-old male presented with blurred vision in his right eye. In the ophthalmic evaluation, there were dispersed keratic precipitates overlying corneal edema. The anterior chamber showed trace ~1+ graded inflammation and an endothelial density decrease. His best-corrected visual acuity and intraocular pressure in the right eye were 0.2 and 34 mmHg, respectively. Paracentesis was performed on the anterior chamber of the right eye to confirm the diagnosis under the suspicion of corneal endotheliitis with trabeculectomy for the intraocular pressure control. Epstein-Barr virus was confirmed using a multiplex polymerase chain reaction (PCR), and oral and eye drops of Acyclovir were used to treat the patient. There was no evidence of a recurrence over 2 years and his intraocular pressure was 12 mmHg and best-corrected visual acuity was maintained at 0.5. CONCLUSIONS: A case of Epstein-Barr virus-related corneal endotheliitis was diagnosed using PCR of the aqueous humor. The patient was treated with an oral antiviral agent and eyedrops without a recurrence.
Key Words: Acyclovir;Endotheliitis;Epstein-Barr Virus


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