Measurement of Precorneal Tear Film Using Scheimpflug Camera and Relationship with Parameters for Dry Eye.

Kang, Na Hee; Park, Yeon Ggoch; Jun, Roo Min

doi:2015.56.11.1699

J Korean Ophthalmol Soc > Volume 56(11); 2015 > Article

Original Article

Journal of the Korean Ophthalmological Society 2015;56(11):1699-1705.
DOI: https://doi.org/10.3341/jkos.2015.56.11.1699 Published online November 15, 2015.

Measurement of Precorneal Tear Film Using Scheimpflug Camera and Relationship with Parameters for Dry Eye.

Na Hee Kang, Yeon Ggoch Park, Roo Min Jun

¹Woorieyes Clinic, Wonju, Korea.
²Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Korea. jrmoph@ewha.ac.kr

샤임플러그 전안부사진기를 이용한 눈물막의 두께 측정 및 건성안 지표와의 관계 분석

강나희¹⋅박연꽃²⋅전루민²

우리안과의원¹, 이화여자대학교 의학전문대학원 안과학교실²

Received: 24 April 2015 • Revised: 8 June 2015 • Accepted: 4 September 2015

Abstract

PURPOSE
To compare the anterior segment parameters including precorneal tear film thickness (PTFT) using Pentacam(R) (Oculus, Wetzlar, Germany) between normal control and dry eye groups and to examine the relationships between the PTFT and other parameters for dry eye. METHODS: The present study included 23 normal controls (31 eyes) and 25 patients with dry eyes (31 eyes). We compared measurements including PTFT, corneal thickness and astigmatism using Pentacam(R) and analyzed the correlations among the PTFT and fluorescein tear break-up time (FBUT), Schirmer I test (without anesthesia), and ocular surface disease index (OSDI). RESULTS: The mean PTFT in dry eyes (21.1 +/- 2.0 microm) was significantly thinner than in normal eyes (37.6 +/- 2.0 microm; p < 0.01). In the dry eye group, the corneal thickness was thicker than in the normal eye group but there were no clinically significant differences. The dry eye group experienced more frequent and severe corneal astigmatism compared with the normal group. OSDI scores showed a weak negative correlation with objective clinical measures of dry eye (FBUT, Schirmer I test) but was not statistically significant. However, OSDI was statistically significantly negatively correlated with PTFT (r = -0.46, p < 0.01). The PTFT showed a weak positive correlation with FBUT and Schirmer I test without statistical significance. CONCLUSIONS: The mean PTFT using Pentacam(R) in the dry eye group was thinner than in the normal group. Additionally, the PTFT was correlated with subjective symptoms. Therefore, the PTFT measurement using Pentacam(R) could be considered a useful method for diagnosis and treatment of dry eye.

Key Words: Dry eye;Fluorescein tear break-up time;Ocular surface disease index;Pentacam(R);Precorneal tear film thickness