| A Case Report of Eyebrow Basal Cell Carcinoma Successfully Treated with 5% Imiquimod Cream. |
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Byeong Soo Kang, Nam Ju Kim, Ho Kyung Choung, Sang In Khwarg |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. khwarg@snu.ac.kr
2Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
3Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea. |
| 5% Imiquimod Cream으로 치료한 눈썹부위 바닥세포암 증례 1예 |
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강병수1⋅김남주1,2⋅정호경1,3⋅곽상인1 |
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서울대학교 의과대학 안과학교실1, 서울대학교 의과대학 분당서울대학교병원 안과학교실2, 서울대학교병원운영 서울특별시보라매병원 안과학교실3 |
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Received: 29 May 2015 • Revised: 22 June 2015 • Accepted: 4 September 2015 |
| Abstract |
PURPOSE
Basal cell carcinoma is the most common malignant neoplasm of the skin. Periorbital basal cell carcinoma needs to be treated for cosmetic improvement and prevention of intraorbital invasion. Although surgical excision is a standard treatment, nonsurgical treatment using imiquimod cream, a topical immunomodulator, has been attempted. The authors report the first case of periorbital basal cell carcinoma successfully treated with imiquimod cream; to the best of our knowledge, similar cases have not been published to date in the Korean ophthalmology journals. CASE SUMMARY: A 73-year-old female visited our hospital for treatment of a biopsy-proven basal cell carcinoma in the right eyebrow. A flat, elevated, 1 x 1 cm-sized mass having central indentation was observed in the centromedial area of the right eyebrow. She was treated with 5% imiquimod cream once daily at night, 5 days per week for 6 weeks. Eight weeks after the treatment with imiquimod cream was discontinued, the mass was flattened and the cilia began to grow on the mass site. Under the impression of a partial regression, an additional 4 weeks of application was recommended. The mass disappeared more and her eyebrow became more normal. At the final follow-up 31 months after treatment, her right eyebrow appeared normal. CONCLUSIONS: Imiquimod cream may be a useful medication which can be used for complex periorbital basal cell carcinomas that are difficult to reconstruct after resection or surgical candidates with poor general condition. |
| Key Words:
Imiquimod cream;Periorbital basal cell carcinoma |
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