J Korean Ophthalmol Soc > Volume 57(1); 2016 > Article
Journal of the Korean Ophthalmological Society 2016;57(1):155-160.
DOI: https://doi.org/10.3341/jkos.2016.57.1.155    Published online January 15, 2016.
A Case of Spontaneous Closure of Macular Hole in Infectious Posterior Uveitis Involving the Fovea.
Min Woo Kim, Dong Yoon Kim, Yoon Jeon Kim, Soo Geun Joe, Joo Yong Lee, June Gone Kim
1Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. junekim@amc.seoul.kr
2Department of Ophthalmology, Chungbuk National University College of Medicine, Cheongju, Korea.
3Department of Ophthalmology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.
중심와를 침범한 감염성 포도막염에서 발생한 황반원공의 자연폐쇄 1예
김민우1⋅김동윤2⋅김윤전1⋅조수근3⋅이주용1⋅김중곤1
울산대학교 의과대학 서울아산병원 안과학교실1, 충북대학교 의과대학 안과학교실2, 울산대학교 의과대학 강릉아산병원 안과학교실3
Abstract
PURPOSE
To report a case of macular hole secondary to presumptive infectious posterior uveitis involving the fovea that spontaneously resolved after medical treatment. CASE SUMMARY: A 33-year-old male visited our clinic for decreased visual acuity in his left eye. He was treated with immunosuppressive therapy including steroid after bone marrow transplantation. Best corrected visual acuity (BCVA) was 0.05 in the left eye. Slit lamp examination showed mild anterior vitritis, and fundus examination showed a macular hole with surrounding whitish infiltration at the fovea. Spectral domain optical coherence tomography (SD-OCT) revealed a full thickness macular hole with surrounding hyper-reflective masses with an infiltration-like appearance involving all retinal layers. Serum anti-toxocara IgG was positive (ELISA), and eosinophil count and immunoglobulin E was elevated. Under diagnosis of presumptive ocular toxocariasis, the patient was treated with albendazole. After medical treatment for toxocariasis, the whitish foveal infiltration became smaller and more discrete. SD-OCT revealed spontaneous closure of the macular hole, and BCVA was improved to 0.4 after a 4-month follow-up. CONCLUSIONS: We report a macular hole complicated by presumptive infectious posterior uveitis that experienced spontaneous closure after medical treatment for underlying infection.
Key Words: Macular hole;Posterior uveitis;Spontaneous closure;Toxocariasis


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