| A Case of Pigmentary Glaucoma Due to Multidrug-Resistant Tuberculosis Treatment. |
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Jae Woo Jung, Seong Ho Jo, Je Hyun Seo, Yun Seong Kim |
1Department of Ophthalmology, Pusan National University Yangsan Hospital, Yangsan, Korea. jazmin2@naver.com
2Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea.
3Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
4Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. |
| 광범위 약제내성 폐결핵 약물치료 중 발생한 색소녹내장 1예 |
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정재우1,2⋅조성호1,2⋅서제현1,2⋅김윤성3,4 |
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양산부산대학교병원 안과학교실1, 부산대학교 의학전문대학원 안과학교실2, 양산부산대학교병원 내과학교실3, 부산대학교 의학전문대학원 내과학교실4 |
Correspondence:
Je Hyun Seo,
Email: jazmin2@naver.com
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Received: 3 July 2015 • Revised: 3 September 2015 • Accepted: 29 October 2015 |
| Abstract |
PURPOSE
To report a case of secondary pigmentary glaucoma due to clofazimine treatment for extensive drug-resistant tuberculosis. CASE SUMMARY: A 23-year-old man presented with blurred vision in both eyes. The patient started to take clofazimine for extensive drug-resistant tuberculosis six months prior, after which his facial skin color changed to a dark-brown. Intraocular pressure (IOP) was 50 mm Hg in the right eye and 48 mm Hg in the left eye. Slit lamp examination revealed corneal edema, opacity, and flare in the anterior chamber in both eyes. A color vision test revealed a mild color defect in both eyes. Visual field (VF) test revealed superior temporal VF loss in the left eye. Gonioscopy revealed open angles with high pigmentation in the trabecular meshwork in both eyes. The patient was diagnosed with pigmentary glaucoma, and maximum tolerated medical therapy was performed. However, the IOP was uncontrolled. Trabeculectomy was performed in both eyes. Postoperative IOP was measured to be 12 mm Hg in both eyes without medication, and visual acuity measured 20/22 in the right eye and 20/17 in the left eye. CONCLUSIONS: To the best of our knowledge, this report is the first case of clofazimine being a possible cause of pigmentary glaucoma in a patient with extensive drug-resistant tuberculosis. |
| Key Words:
Clofazimine;Extensive drug-resistant tuberculosis;Pigmentary glaucoma;Trabeculectomy |
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