| Effect of a Preservative-free Dorzolamide/Timolol Fixed Combination on Elevated Intraocular Pressure after Vitrectomy. |
|
Sung Hoon Lee, Wonseok Lee, Gong Je Seong, Suk Ho Byeon, Sung Soo Kim, Hyoung Jun Koh, Sung Chul Lee, Min Kim |
1Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. Minkim76@gmail.com
2The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. |
| 유리체 절제술 후 안압 상승 환자에서 무보존제 도르졸라미드-티몰롤 복합제제의 안압 하강효과 |
|
이성훈1⋅이원석1⋅성공제1⋅변석호1⋅김성수2⋅고형준2⋅이성철2⋅김 민1 |
|
연세대학교 의과대학 강남세브란스병원 안과학교실1, 연세대학교 의과대학 안과학교실 시기능개발 연구소2 |
Correspondence:
Min Kim,
Email: Minkim76@gmail.com
|
|
Received: 10 March 2016 • Revised: 13 May 2016 • Accepted: 29 August 2016 |
| Abstract |
PURPOSE
To verify the effect of preservative-free Dorzolamide/Timolol fixed combination (PFDTC) on intraocular pressure (IOP) elevation after vitrectomy. METHODS: We retrospectively reviewed medical records of 33 patients who used PFDTC after pars plana vitrectomy. All patients' visual acuity and IOP was measured and symptoms of conjunctival irritation were investigated through survey and slit lamp examination. RESULTS: Before vitrectomy, the mean IOP was 13.6 ± 4.4 mm Hg which was elevated to 31.7 ± 5.4 mm Hg after vitrectomy (p < 0.001) and applying eyedrop lowered the mean IOP to 17.2 ± 7.0 mm Hg (p < 0.001). Regardless of tamponade material type, all elevated IOP decreased (p < 0.001) and the IOP of all 33 eyes did not rise to over 30 mm Hg again. No additional surgery for IOP control was needed during two-month follow-up period. Of the 33 patients using PFDTC, patients who felt discomfort were five (15.2%) and no patients showed side effects severe enough to stop use of eyedrop. CONCLUSIONS: PFDTC is an anti-glaucomatic agent which can reduce the IOP by inhibiting aqueous humor production. Without need for additional surgery, the eyedrop can effectively lower elevated post-vitrectomy IOP, with expectation of good patient compliance due to low risk of conjunctival irritation. |
| Key Words:
Cosopt-S®;Eyedrops;Intraocular pressure;Preservative-free;Vitrectomy |
|
PDF Links
Full text via DOI
Download Citation
