J Korean Ophthalmol Soc > Volume 58(3); 2017 > Article
Journal of the Korean Ophthalmological Society 2017;58(3):276-282.
DOI: https://doi.org/10.3341/jkos.2017.58.3.276    Published online March 15, 2017.
Comparison of Central Corneal Thickness Measured by Swept-source Optical Coherence Tomography and Ultrasound Pachymetry.
Woo Beom Shin, Hyun Kyo Jeong, Min Kyo Kim, Hong Seok Kim, Jun Mo Lee, Chan Yun Kim, Ji Hyun Kim
1Siloam Eye Hospital, Seoul, Korea. jhkim@siloam.co.kr
2The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
파장가변 빛간섭단층촬영계와 초음파 각막두께측정계를 이용해 측정한 중심각막두께의 비교
신우범1,2⋅정현교1,2⋅김민교1,2⋅김홍석1⋅이준모1⋅김찬윤2⋅김지현1
실로암 안과병원1, 연세대학교 의과대학 안과학교실 시기능개발연구소2
Correspondence:  Ji Hyun Kim,
Email: jhkim@siloam.co.kr
Received: 3 November 2016   • Revised: 30 January 2017   • Accepted: 26 February 2017
Abstract
PURPOSE
To analyze and compare ultrasound pachymetry (USP) with a more recently adopted device, the intra ocular lens (IOL) master 700, which are both used to measure central corneal thickness. METHODS: The central corneal thickness was measured in 24 eyes of 12 glaucoma patients and in 83 eyes of 42 normal patients. First, the IOL master 700 was used to measure the central corneal thickness, followed by measurements taken using USP later. The results were analyzed using a paired t-test. We analyzed the agreement and the correlations between the two test devices by using Bland-Altman plots and the Pearson correlation test. To evaluate the reproducibility, measurements with the IOL master 700 were taken twice for a few normal patients within a small time interval. RESULTS: Via the IOL master 700, the thickness of the central cornea showed a high reproducibility and repeatability, demonstrating 2.7 ± 1.7 µm for the test-retest variability, 6.78% for the coefficient of variation, and 0.997 for the intraclass correlation value. The mean measurements using USP and the IOL master 700 are 554.4 ± 37.4 µm and 551.1 ± 37.1 µm, respectively, showing that the IOL master 700 measured significantly smaller values than USP with a p-value < 0.001. The deviations between the two methods are scattered throughout the 95% confidence interval. According to the Pearson correlation test, the measured values of the two test devices were found to have a highly positive correlation (r = 0.977, p < 0.0001). CONCLUSIONS: This study demonstrated that the central corneal thickness (CCT) measured via the IOL master was significantly thinner than that of USP, and the two test devices had a high correlation and good agreement. The CCT value measured via the IOL master 700 also exhibited high reproducibility.
Key Words: Central corneal thickness;Ultrasound pachymetry;IOL master 700


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