| Ocular Side Effects Induced by 0.25% Alcaftadine Ophthalmic Solution. |
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Jong Soo Lee, Jong Moon Park, Hyun Kyung Cho, Su Jin Kim, Hyoun Do Huh, Young Min Park |
1Department of Ophthalmology, Pusan National University School of Medicine, Yangsan, Korea.
2Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. loveis293@naver.com
3Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Changwon, Korea. |
| 0.25% 알카프타딘 점안액 사용으로 인한 눈 부작용 |
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이종수1⋅박종문2,3⋅조현경2,3⋅김수진2,3⋅허현도2,3⋅박영민2,3 |
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부산대학교 의학전문대학원 안과학교실1, 경상대학교 의학전문대학원 안과학교실2, 창원 경상대학교병원 안과3 |
Correspondence:
Young Min Park,
Email: loveis293@naver.com
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Received: 26 January 2017 • Revised: 16 February 2017 • Accepted: 18 April 2017 |
| Abstract |
PURPOSE
To report a case series of patients experiencing side effects of 0.25% alcaftadine eye drops and to analyze the possible reasons for the side effects. CASE SUMMARY: Medical records of 90 patients who had a history of alcaftadine eye drop use were retrospectively analyzed. Eight out of the 90 patients (8.9%) showed ocular side effects that required discontinuation of the alcaftadine eye drops. All eight cases of alcaftadine side effects showed palpebral and bulbar conjunctival injection, watery discharge, and lid swelling. During additional history collection, all patients with alcaftadine side effects confessed of overuse (more than twice/day) of the eye drops. Anticipation for fast symptom relief was the main reason for the alcaftadine overuse. In all side effect cases, patients were asked to stop alcaftadine eye drops and use preservative-free artificial tears and steroid eye drops. After discontinuation of 0.25% alcaftadine eye drops, regression of palpebral and bulbar conjunctival injection and lid swelling was observed. CONCLUSIONS: Overuse of 0.25% alcaftadine eye drops can induce ocular surface toxicity possibly due to toxicity of drug itself. The possible side effects of overuse of 0.25% alcaftadine eye drops should be fully explained to all patients before use. |
| Key Words:
Alcaftadine;Allergy;Conjunctivitis;Toxicity |
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