| A Comparative Histopathological Study of Lens Capsule and Epithelial Cells in Various Types of Cataract. |
|
Young Min Park, Byung Gun Park, In Ho Lee, Jong Soo Lee |
1Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea.
2Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Changwon, Korea.
3Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
4Department of Ophthalmology, Pusan National University School of Medicine, Yangsan, Korea. jongsool@pusan.ac.kr |
| 다양한 백내장에서 수정체 전낭 및 상피세포의 조직병리학적 비교연구 |
|
박영민1,2⋅박병건3⋅이인호4⋅이종수4 |
|
경상대학교 의학전문대학원 안과학교실1, 창원경상대학교병원 안과2, 인제대학교 의과대학 부산백병원 안과학교실3, 부산대학교 의학전문대학원 안과학교실4 |
Correspondence:
Jong Soo Lee,
Email: jongsool@pusan.ac.kr
|
|
Received: 1 June 2017 • Revised: 14 July 2017 • Accepted: 28 July 2017 |
| Abstract |
PURPOSE
To evaluate the histopathological changes of anterior capsule and lens epithelial cells in various types of cataract. METHODS: Patients scheduled for cataract surgery of phacoemulsification with intraocular lens implantation were enrolled in this study. Anterior capsule tissues sized 5 mm were obtained at the time of continuous curvilinear capsulorhexis during surgery. Histological examination of the obtained tissue was performed by transmission electron microscope. RESULTS: Nuclear cataract showed a uniform cuboidal monolayer of epithelial cells firmly attached to the anterior capsule. But, the mitochondria, Golgi apparatus, and endoplasmic reticulum were damaged and replaced with vacuoles. Anterior subcapsular cataract showed multilayers of epithelial cells with irregular intracellular structures. Epithelial cells of mature cataract were severely damaged and detached from the anterior capsule, accompanied by expansion of intra-cellular space and a large amount of vacuoles. Epithelial cells were irregular and severely damaged, and intracellular structures were hardly observed in traumatic cataract. Deposition of pseudoexfoliation materials on the anterior capsule was observed in pseudoexfoliation cataract. CONCLUSIONS: Changes in epithelial cells caused by fluid accumulation and electrolyte imbalance in the lens attributes more to cataract formation than do changes the in lens capsule. |
| Key Words:
Anterior capsule;Cataract;Lens epithelial cell;Transmission electron microscope |
|
PDF Links
Full text via DOI
Download Citation
