J Korean Ophthalmol Soc > Volume 55(6); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(6):840-846.
DOI: https://doi.org/10.3341/jkos.2014.55.6.840    Published online June 15, 2014.
Changes in Subfoveal Choroidal Thickness in Malignant Hypertension Patients.
Ji Won Kim, Yun Taek Kim
1Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Korea. jjongofhim@hanmail.net
2Ewha Womans University Global Top 5 Research Program, Seoul, Korea.
악성고혈압 환자에서 황반 하 맥락막 두께 변화
Department of Ophthalmology, Ewha Womans University School of Medicine1, Seoul, Korea
Ewha Womans University Global Top 5 Research Program2, Seoul, Korea
To evaluate changes in subfoveal choroidal thickness in patients with malignant hypertension. METHODS: A total of 12 eyes of six malignant hypertension patients were included in the present study. Intraocular pressure, blood pressure (systolic and diastolic), and choroidal thickness were measured before and after blood pressure control. Choroidal thickness was measured using enhanced depth imaging optical coherence tomography (EDI-OCT). The changes in choroidal extravascular density of the EDI-OCT image after blood pressure control were evaluated by comparing brightness values obtained with Adobe Photoshop software. RESULTS: The subfoveal choroidal thickness (SFCT) of malignant hypertension patients was 412.63 +/- 66.55 microm (mean +/- SD), which was thicker than in normal patients. After blood pressure control, SFCT decreased significantly to 356.96 +/- 59.08 microm (mean +/- SD) (p = 0.002). The choroidal extravascular density of the EDI-OCT image decreased after blood pressure control (p = 0.002), and the mean change was 17.21 +/- 7.56. CONCLUSIONS: The choroid is thickened in patients with malignant hypertension, and its thickness decreases after blood pressure control. This suggests that changes in blood pressure may affect choroidal thickness.
Key Words: Choroidal thickness;Hypertensive retinopathy;Malignant hypertension;OCT

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