A Case of Recurrent Uveitis in Autoimmune Liver Disease.

Kim, Ji Eob; Choo, Hun Gu; Yoon, Ie Na

doi:2014.55.8.1257

J Korean Ophthalmol Soc > Volume 55(8); 2014 > Article

Case Report

Journal of the Korean Ophthalmological Society 2014;55(8):1257-1260.
DOI: https://doi.org/10.3341/jkos.2014.55.8.1257 Published online August 15, 2014.

A Case of Recurrent Uveitis in Autoimmune Liver Disease.

Ji Eob Kim, Hun Gu Choo, Ie Na Yoon

Department of Ophthalmology, Yonsei University Wonju College of Medicine, Wonju, Korea. bswhitey@hanmail.net

자가면역성 간질환과 동반된 재발성 포도막염 1예

김지업⋅추헌구⋅윤이나

Department of Ophthalmology, Yonsei University Wonju College of Medicine, Wonju, Korea

Abstract

PURPOSE
To report a case of recurrent uveitis associated with autoimmune liver disease. CASE SUMMARY: A 50-year-old female with severe fatigue and arthritis visited the ophthalmology department due to decreased visual acuity and discomfort in her right eye for ten days. She had intermittent injection and blurred vision in both eyes for 30 years. Slit lamp examination of her right eye showed keratic precipitates, pigment deposits on the anterior capsule of the lens and anterior chamber cells; fundus examination was normal without any sign of chorioretinitis. Inflammatory reaction was improved after steroid and cycloplegic eye drop treatment. Two months later, her left eye developed anterior uveitis. Inflammation was well controlled with steroid and cycloplegic eye drop treatment. To evaluate the cause of uveitis and associated systemic disease, serological testing was performed, and abnormal elevation of liver enzymes was detected. The patient was referred to the Gastroenterology Department and diagnosed with autoimmune liver disease. Oral ursodeoxycholic acid was prescribed. Liver function profile improved to normal range, and the patient is currently under routine follow-up with no sign of recurrent uveitis. CONCLUSIONS: When a patient with recurrent uveitis presents symptoms such as nausea, fatigue, abdominal pain, jaundice or abnormal liver profile, association with autoimmune liver disease should be considered.

Key Words: Autoimmune hepatitis;Autoimmune liver disease;Uveitis