J Korean Ophthalmol Soc > Volume 55(9); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(9):1313-1319.
DOI: https://doi.org/10.3341/jkos.2014.55.9.1313    Published online September 15, 2014.
Choroid in Myopic Choroidal Neovascularization Measured Using SD-OCT.
Jin Sung Park, Young Wook Cho, Ji Hye Jang
Department of Ophthalmology, Daegu Fatima Hospital, Daegu, Korea. mjmom@naver.com
근시성 맥락막 신생혈관 환자에서 스펙트럼 영역 빛간섭단층촬영으로 측정한 맥락막
박진성⋅조영욱⋅장지혜
Department of Ophthalmology, Daegu Fatima Hospital, Daegu, Korea
Abstract
PURPOSE
Using the spectral domain optical coherence tomography (SD-OCT), we studied the difference in the choroidal morphology between the choroidal neovascularization (CNV) area and the area surrounding CNV. METHODS: This retrospective study consisted of 19 patients with myopic CNV lesion in eye; fellow eyes were used as controls. All eyes were analyzed by measuring the choroidal thickness and large choroidal vessel size using SD-OCT. Eyes with CNV were divided into groups; the neovascular lesion was defined as group 1, the surrounding area as group 2. Subfovea of the fellow eye was defined as group 3. RESULTS: The choroidal thickness was 80.00 +/- 68.31 in group 1, 63.44 +/- 67.75 in group 2 and 71.11 +/- 65.69 microm in group 3. There was a significant difference between group 1 and group 2 (p = 0.038). There were no significant differences between group 1 and 3 or between group 2 and 3 (p = 0.365, p = 0.314). The large choroidal vessel size was 57.47 +/- 39.78 in group 1, 40.45 +/- 34.69 in group 2 and 45.63 +/- 37.00 microm in group 3. There was a significant difference between group 1 and group 2 (p = 0.025). There were no significant differences between group 1 and 3 or between group 2 and 3 (p = 0.123, p = 0.325). CONCLUSIONS: Choroidal thickness and large choroidal vessel size at the center of the CNV were greater than in the area surrounding CNV. The results suggest that although the CNVs were due to a thinned choroid caused by severe choroidal ischemia, the development of CNV requires maintenance of choriocapillaris and large choroid vessels.
Key Words: Choroidal thickness;Large choroidal vessel size;Myopic choroidal neovascularization;SD-OCT


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