J Korean Ophthalmol Soc > Volume 56(1); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(1):6-12.
DOI: https://doi.org/10.3341/jkos.2015.56.1.6    Published online January 15, 2015.
Relationship between Dry Eye Parameters and Anterior Corneal Higher-Order Aberrations Measured by Two Different Instruments.
Ah Ran Cho, Na Hee Kang, Roo Min Jun
Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Korea. jrmoph@ewha.ac.kr
건성안 지표와 서로 다른 두 기기로 측정된 전면 각막 고위수차의 관계 분석
Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Korea
To compare the corneal first surface higher-order aberrations (HOAs) of normal subjects and patients with dry eye using KR-1W(R) (Topcon Corp., Tokyo, Japan) and Pentacam(R) HR (Oculus Inc., Dutenhofen, Germany). We analyzed the relationship between the aberrations and the diagnostic parameters of dry eye. METHODS: We evaluated anterior corneal HOAs in 71 normal eyes and 71 dry eyes using KR-1W(R) and Pentacam(R). Dry eye patients were examined for fluorescein staining, tear break-up time (TBUT), and Schirmer I test. Ocular Surface Disease Index (OSDI) was used for assessment of subjective symptoms in dry eye patients. RESULTS: HOAs measured by both instruments were greater in the dry eye group than in the control group, although HOAs using KR-1W(R) only achieved statistical significance. The anterior corneal HOAs measured by the 2 instruments were significantly correlated with superficial punctate keratitis. Moreover, TBUT and the Shirmer I test negatively correlated, and OSDI positively correlated, with anterior corneal HOAs. CONCLUSIONS: The HOAs in patients with dry eye were significantly different from controls and tended to increase with disease severity. KR-1W(R) might be more useful than Pentacam(R) to detect tear film instabilities.
Key Words: Anterior corneal higher-order aberrations;Dry eye;HOAs;KR-1W(R);Pentacam(R)

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