| Comparative Study of Hugel-tox(R) versus Botox(R) for the Treatment of Essential Blepharospasm. |
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Jee Hye Lee, Su Kyung Jung, Ji Sun Baik, Suk Woo Yang |
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Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. yswoph@catholic.ac.kr |
| 본태눈꺼풀연축 환자에서 휴젤톡스와 보톡스 효과 비교 |
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이지혜⋅정수경⋅백지선⋅양석우 |
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가톨릭대학교 의과대학 서울성모병원 안과 및 시과학교실 |
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Received: 29 August 2014 • Revised: 17 December 2014 • Accepted: 23 April 2015 |
| Abstract |
PURPOSE
To compare clinical efficacy and duration of Hugel-tox(R) (also known as Botulax(R)) and Botox(R) for the treatment of essential blepharospasm. METHODS: A total of 48 patients who were injected with Hugel-tox(R) (17 females, 7 males) or Botox(R) (18 females, 6 males) from February 2013 to October 2013 were enrolled in the present study. Changes in eyelid closing force and Scott grade before and after injection were analyzed. Adverse events were also evaluated. RESULTS: There were no significant differences between the Hugel-tox(R) and Botox(R) groups in clinical efficacy and duration. Before and after injection, changes in Scott grade (Hugel-tox(R): -1.17 +/- 0.70, Botox(R): -1.21 +/- 0.72, p = 0.840), changes in eyelid closing force (Hugel-tox(R): -1.38 +/- 0.58, Botox(R): -1.17 +/- 0.56, p = 0.212) and duration (Hugel-tox(R): 116.08 +/- 22.12 days, Botox(R): 126.92 +/- 38.94 days, p = 0.242) were shown. No serious adverse events were found in either group. CONCLUSIONS: Hugel-tox(R) showed nearly equal efficacy and duration compared with Botox(R). |
| Key Words:
Botox;Essential blepharospasm;Hugel-tox |
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