J Korean Ophthalmol Soc > Volume 56(7); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(7):1012-1019.
DOI: https://doi.org/10.3341/jkos.2015.56.7.1012    Published online July 15, 2015.
Comparison of Eye Protection Methods of Ointment Instillation under General Anesthesia.
Seung Hoon Yoo, Hyuna A Kim, Sang Il Ahn, Soon Im Kim, Jin Kwon Chung
1Department of Ophthalmology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. schcornea@schmc.ac.kr
2Department of Ophthalmology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
3Department of Ophthalmology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.
4Department of Anesthesiology and Pain Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
전신 마취 중 안구 보호를 위한 서로 다른 안 연고의 효과 비교
순천향대학교 의과대학 순천향대학교 서울병원 안과학교실1, 순천향대학교 의과대학 순천향대학교 부천병원 안과학교실2, 순천향대학교 의과대학 순천향대학교 천안병원 안과학교실3, 순천향대학교 의과대학 순천향대학교 서울병원 마취통증의학교실4
Received: 27 February 2015   • Revised: 11 May 2015   • Accepted: 4 June 2015
To compare the efficacy of 3 different eye ointment instillations with eyelid taping and eyelid taping alone to prevent eye complications during surgery under general anesthesia. METHODS: A total of 296 eyes of 148 patients who underwent general anesthesia for at least 60 minutes were randomly assigned to 1 of the following 4 groups: group A, eyelid taping alone; group B, eyelid taping with solcoseryl ointment; group C, eyelid taping with carbomer ointment; group D, eyelid taping with lanolin ointment. Schirmer test, tear film break-up time (TF-BUT), conjunctival hyperemia scale (CHS), National Eye Institute corneal staining scale (NSS), and ocular surface disease index (OSDI) were prospectively evaluated before and after general anesthesia. RESULTS: TF-BUT was significantly increased in the group B compared with the preoperative value (p = 0.035). CHS was significantly decreased in all 3 ointment groups (p < 0.05) after general anesthesia and the degree was significantly higher in groups B and C (p < 0.001). No corneal abrasion developed after general anesthesia. However, corneal erosion developed in 20 eyes of previously healthy subjects; 8 eyes (12.5%) in group A, 0 eye (0%) in group B, 2 eyes (2.5%) in group C, and 10 eyes (13.9%) in group D. The occurrence rates of new lesions were significantly lower in groups B and C (p = 0.035). CONCLUSIONS: Both eyelid taping alone and eyelid taping with eye ointment are effective protection methods against corneal abrasion during operation under general anesthesia. Eye ointment instillation together with eyelid taping shows not only improvement of subjective symptoms but also improvement of objective ocular surface parameters proving to be an effective ocular protection during general anesthesia.
Key Words: Corneal abrasion;Corneal erosion;Eyelid taping;General anesthesia;Ointment

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