Risk Factors and Clinical Manifestations of Ocular Hypertension after Primary Repair of Open Globe Injury.

Kang, Yeon Soo; Park, Sang Woo

doi:2015.56.8.1242

J Korean Ophthalmol Soc > Volume 56(8); 2015 > Article

Original Article

Journal of the Korean Ophthalmological Society 2015;56(8):1242-1247.
DOI: https://doi.org/10.3341/jkos.2015.56.8.1242 Published online August 15, 2015.

Risk Factors and Clinical Manifestations of Ocular Hypertension after Primary Repair of Open Globe Injury.

Yeon Soo Kang, Sang Woo Park

Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. exo70@naver.com

개방성 안구열상의 수술 후 발생한 고안압증의 위험인자 및 임상 양상

강연수⋅박상우

전남대학교 의과대학 안과학교실

Received: 16 January 2015 • Revised: 23 April 2015 • Accepted: 1 July 2015

Abstract

PURPOSE
To investigate the risk factors and clinical manifestations of ocular hypertension (HTN) after repair of open globe injury (OGI). METHODS: In a retrospective study of 284 patients who underwent primary repair of open globe injury at the day of trauma, best corrected visual acuity (BCVA) at the time of trauma and 6 months postoperatively, length of laceration, location of laceration and mean intraocular pressure (IOP) at 1 month after primary repair were analyzed. Presence of iris injury, lens injury, intraocular foreign body (IOFB) and vitreous hemorrhage (VH) were also analyzed. Ocular hypertension was defined as elevation of IOP greater than or equal to 21 mm Hg over 3 measurements. RESULTS: Fourteen (4.93%) of 284 patients had ocular hypertension. BCVA (log MAR) at the time of trauma in the ocular HTN group was significantly worse than in the normal IOP group (2.43 +/- 1.04 and 1.76 +/- 1.30, respectively, p = 0.033). In the multivariate analysis, ocular HTN increased significantly with IOFB (p = 0.038; odds ratio [OR], 3.584; 95% confidence interval [CI], 1.075-11.941) and VH (p = 0.028; OR, 3.971; 95% CI, 1.157-13.624). BCVA increased significantly after repair in both groups and mean IOP was well controlled after medical therapy (9 eyes) or surgical treatment (5 eyes) in the ocular HTN group (28.1 +/- 4.7 and 15.8 +/- 3.8, respectively, p < 0.01). CONCLUSIONS: Ocular HTN increased significantly with IOFB and VH at the time of trauma after repair of OGI and can be effectively treated by medication or surgical approach.

Key Words: Intraocular pressure;Ocular hypertension;Open globe injury