| Correlation between Macular GCIPL Thickness and Visual Acuity after Resolution of Diabetic Macular Edema. |
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Ji Man Park, Young Chang Lee, Seong Taeck Kim |
1Department of Ophthalmology, Chosun University School of Medicine, Gwangju, Korea. s20age@hanmail.net
2I Clinic, Gwangju, Korea. |
| 당뇨황반부종 호전 후 황반부 신경절세포-내망상층 두께와 시력과의 관계 |
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박지만1⋅이영창2⋅김성택1 |
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조선대학교 의학전문대학원 안과학교실1, 아이안과2 |
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Received: 27 March 2015 • Revised: 22 June 2015 • Accepted: 14 August 2015 |
| Abstract |
PURPOSE
To evaluate the peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGCIPL) thickness in eyes with resolved diabetic macular edema (DME). METHODS: Twenty eyes of diabetic retinopathy patients with resolved DME (DME group) after treatment, and 20 eyes of diabetic retinopathy patients without DME (no-DME group) were included in this study. The pRNFL thickness, mGCIPL thickness and central macular thickness (CMT) were measured using spectral-domain optical coherence tomography (SD-OCT). Analyses were performed to determine the correlation between the different thicknesses and the visual function. RESULTS: No significant difference in mean CMT was observed between the DME and no-DME groups. Average pRNFL thickness in the DME group was thicker than in the no-DME group (p = 0.003). Average mGCIPL thickness in the DME group was thinner than in the no-DME group (p = 0.030). Final visual acuity was significantly correlated with average mGCIPL thickness and minimum mGCIPL thickness, but not pRNFL thickness and CMT in the DME group. CONCLUSIONS: mGCIPL thickness decreased in the DME group compared with the no-DME group and was correlated with the visual acuity. These results suggested that inner retinal injury in patients with DME might lead to poor visual outcome after treatment. |
| Key Words:
Diabetic macular edema (DME);Ganglion cell-inner plexiform layer (GCIPL);Optical coherence tomography (OCT) |
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