J Korean Ophthalmol Soc > Volume 56(10); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(10):1489-1496.
DOI: https://doi.org/10.3341/jkos.2015.56.10.1489    Published online October 15, 2015.
Clinical Outcomes of Descemet's Membrane Endothelial Keratoplasty: A 1-Year Retrospective Study.
Gyu Le Han, Joo Hyun, Dong Hui Lim, Eui Sang Chung, Tae Young Chung
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. tychung@skku.edu
데스메막 각막내피이식술 후의 1년 임상결과
한겨레⋅현 주⋅임동희⋅정의상⋅정태영
성균관대학교 의과대학 삼성서울병원 안과학교실
Received: 17 April 2015   • Revised: 4 June 2015   • Accepted: 14 August 2015
Abstract
PURPOSE
To evaluate the 1-year results of Descemet's membrane endothelial keratoplasty (DMEK) in Korea. METHODS: The medical records of 9 patients (10 eyes) with endothelial disease who underwent DMEK from January 2012 to December 2013, and were followed up for more than 12 months were reviewed retrospectively. RESULTS: In 8 eyes with successful results after surgery, best corrective visual acuity (BCVA) was significantly improved from 1.64 +/- 0.21 (log MAR, mean) to 0.35 +/- 0.22 at 1 month and was maintained at 12 months (p = 0.012, Wilcoxon signed ranks test). BCVA at postoperative 3, 6 and 12 months were gradually increased (0.25 +/- 0.23, 0.20 +/- 0.17 and 0.16 +/- 0.17 log MAR). Endothelial cell counts were 1,996 +/- 528/mm2, 1,564 +/- 174/mm2 and 1,463 +/- 541/mm2, 1,205 +/- 358/mm2 at 1, 3, 6, and 12 months after surgery, tended to decrease but showed no statistical significance. There was no statistical difference in astigmatism before and 3 months after the operation (3.32 +/- 2.36 diopter and 2.57+/- 1.44 diopter). Primary graft failure occurred in 2 eyes and 1 received reoperation. Total detachment was found in 1 eye. CONCLUSIONS: The 1-year results of DMEK showed fast visual recovery which was maintained for 12 months. DMEK may be a very efficient option for the surgical management of corneal endothelial disease.
Key Words: Cornea;DMEK;Endothelial keratoplasty


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