Tear Meniscus Evaluation Using Optical Coherence Tomography in Meibomein Gland Dysfunction Patients.

Jeon, Soo Ji; Baek, Ji Won; Doh, Sang Hee; Chung, Sung Kun

doi:2015.56.11.1684

J Korean Ophthalmol Soc > Volume 56(11); 2015 > Article

Original Article

Journal of the Korean Ophthalmological Society 2015;56(11):1684-1691.
DOI: https://doi.org/10.3341/jkos.2015.56.11.1684 Published online November 15, 2015.

Tear Meniscus Evaluation Using Optical Coherence Tomography in Meibomein Gland Dysfunction Patients.

Soo Ji Jeon, Ji Won Baek, Sang Hee Doh, Sung Kun Chung

¹Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
²Department of Ophthalmology and Visual Science, St. Paul's Hospital, College of Medicine, The Catholic University of Korea2, Seoul, Korea. eyedoc@catholic.ac.kr

마이봄샘 기능 이상 환자에서 빛간섭단층촬영을 이용한 눈물띠 분석

전수지¹⋅백지원²⋅도상희²⋅정성근²

가톨릭대학교 의과대학 여의도성모병원 안과 및 시과학교실¹, 가톨릭대학교 의과대학 성바오로병원 안과 및 시과학교실²

Received: 27 February 2015 • Revised: 15 May 2015 • Accepted: 21 August 2015

Abstract

PURPOSE
This study compared tear meniscus parameters between normal control, aqueous tear deficient dry eye, and meibomein gland dysfunction groups using Fourier-domain optical coherence tomography (FD-OCT). METHODS: This study included 33 normal eyes, 79 aqueous tear-deficient dry eyes (ATD), and 48 meibomein gland dysfunction dry eyes (MGD). Following routine examination including Schirmer test, tear break-up time, corneal staining, and tear meniscus parameters such as tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA) were obtained using FD-OCT. The differences among groups were assessed. RESULTS: The averages of TMH, TMD, and TMA were 295.58 +/- 58.36 microm, 166.67 +/- 30.43 microm, and 0.0360 +/- 0.01100 mm2 in normal eyes, respectively, 226.43 +/- 42.18 microm, 147.44 +/- 38.38 microm, and 0.0209 +/- 0.01015 mm2 in ATD, respectively, 272.81 +/- 64.21 microm, 159.37 +/- 44.05 microm, and 0.0295 +/- 0.01271 mm2 in MGD, respectively. Tear meniscus parameters were significantly lower in ATD. Tear meniscus parameters in MGD were higher than ATD and lower than normal eyes, but the TMA was the only statistically significant value. CONCLUSIONS: Although tear meniscus parameters in MGD were higher than ATD, they could not be distinguished from normal eyes. Tear meniscus evaluation using FD-OCT could be a useful measurement system in classification and treatment choice for dry eye patients.

Key Words: Dry eye syndrome;Meibomian gland dysfunction;Optical coherence tomography;Tear meniscus