J Korean Ophthalmol Soc > Volume 53(8); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(8):1167-1171.
DOI: https://doi.org/10.3341/jkos.2012.53.8.1167    Published online August 15, 2012.
A Case of Keratitis Caused by Combined Infection of Multidrug-Resistant Acinetobacter Baumannii and Candida Parapsilosis.
Jae Kwang Choi, In Hyuk Kim, Jeong Won Seo
Department of Ophthalmology, Sahmyook Medical Center, Seoul, Korea. virgo901@hanmail.net
항생제 다제내성 아시네토박터 바우마니와 칸디다 파라프실로시스가 복합감염된 각막염 1예
최재광⋅김인혁⋅서정원
Department of Ophthalmology, Sahmyook Medical Center, Seoul, Korea
Abstract
PURPOSE
To report a case of keratitis caused by Acinetobacter baumannii and Candida parapsilosis in a patient using 0.5% levofloxacin and 0.1% fluorometholone for an extended period of time. CASE SUMMARY: A 55-year-old male patient in the neurosurgery department with conjunctival injection and discharge in his left eye was consulted for ophthalmic evaluation and treatment. He was hospitalized in the state of akinetic mutism and given 0.5% levofloxacin and 0.1% fluorometholone for 2 years. On slit-lamp examination, a 3.5 x 4.5-mm dense stromal infiltrate with an overlying epithelial defect was observed. Corneal scraping culture revealed multidrug-resistant A. baumannii and C. parapsilosis. According to the susceptibility result, the patient was treated with topical 10% piperacillin/tazobactam and 0.125% amphotericin B hourly. The corneal ulcer healed gradually with corneal opacity remaining after 8 weeks of treatment. CONCLUSIONS: The authors of the present study report a case of treated multidrug-resistant A. baumannii and C. parapsilosis keratitis in a patient using topical antibiotics and steroid for an extended period of time.
Key Words: Acinetobacter baumannii;Candida parapsilosis;Combined infection;Keratitis;Multidrug-resistant


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