| The Effect of Hemodialysis on Intraocular Pressure, Retinal Nerve Fiber Layer Thickness and Corneal Thickness. |
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Yong Seok Kang, Young Hoon Hwang, Jae Suk Kim, Joo Hwa Lee |
1Department of Ophthalmology, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. joohlee@paik.ac.kr
2Myung-Gok Eye Research Institute, Department of Ophthalmology, Kim's Eye Hospital, Konyang University, Daejeon, Korea. |
| 혈액투석이 안압, 망막신경섬유층 두께 및 각막두께에 미치는 영향 |
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강용석1⋅황영훈2⋅김재석1⋅이주화1 |
Department of Ophthalmology, Inje University Sanggye Paik Hospital, Inje University College of Medicine1, Seoul, Korea
Myung-Gok Eye Research Institute, Department of Ophthalmology, Kim’s Eye Hospital, Konyang University2, Daejeon, Korea |
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| Abstract |
PURPOSE
To compare the intraocular pressure (IOP), retinal nerve fiber layer (RNFL) thickness and central corneal thickness (CCT) in healthy individuals and patients with chronic renal failure (CRF) undergoing hemodialysis, and to evaluate the changes in each parameter before and after hemodialysis in patients with CRF. METHODS: Thirty-six eyes of 36 patients with CRF undergoing hemodialysis were included in the hemodialysis group and 54 eyes of 54 healthy subjects were recruited as the control group. All subjects underwent a complete eye examination, including best-corrected visual acuity (BCVA), slit lamp examination, dilated funduscopic examination, gonioscopy, automated perimetry, IOP measurement, corneal pachymetry, and evaluation of RNFL thickness. In the hemodialysis group, IOP, RNFL thickness, and CCT were measured again within 1 hour of hemodialysis. RESULTS: Age, sex, BCVA, cup-to-disc ratio, IOP, and CCT were not statistically different between the 2 groups. The RNFL of the hemodialysis group was statistically significantly thinner than the control group (p < 0.001). The IOP decreased from 16.52 +/- 2.95 mm Hg to 14.88 +/- 2.03 mm Hg after hemodialysis (1.63 +/- 3.27 mm Hg; p = 0.005). The changes in RNFL thickness and CCT were not statistically significant (p = 0.148, p = 0.352). CONCLUSIONS: In CRF patients with hemodialysis, RNFLs were thinner in the control group and hemodialysis induced significant IOP reduction. The results from the present study should be considered for the proper evaluation of ocular disorders in CRF patients with hemodialysis. |
| Key Words:
Central corneal thickness;Chronic renal failure;Hemodialysis;Intraocular pressure;Retinal nerve fiber layer thickness |
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