J Korean Ophthalmol Soc > Volume 54(2); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(2):199-209.
DOI: https://doi.org/10.3341/jkos.2013.54.2.199    Published online February 28, 2013.
Anterior Elevation Changes Following Corneal Crosslinking for Keratoconus.
Ji Ho Yang, Kyung Hyun Jin
Department of Ophthalmology, Kyung Hee University School of Medicine, Seoul, Korea. khjinmd@khmc.or.kr
각막 교차결합술을 시행받은 원추각막 환자에서 각막전면높이 변화에 따른 결과 분석
양지호⋅진경현
Department of Ophthalmology, Kyung Hee University School of Medicine, Seoul, Korea
Abstract
PURPOSE
To report the results according to anterior elevation changes following corneal crosslinking (CXL) treatment for keratoconus. METHODS: The present retrospective study included 14 patients (15 eyes) with progressive keratoconus who underwent CXL with a follow-up of 12 months. Patients were classified into 2 groups according to pre and postoperative anterior elevation difference maps. On the preoperative anterior elevation map, distances from maximum anterior elevation to pupil center were compared between the 2 groups. The outcome of best correct visual acuity (BCVA), maximum keratometry and parameters of corneal topography were compared between the 2 groups before CXL as well as 6 and 12 months after CXL. RESULTS: The anterior elevation changes were classified as group 1 (-7.88 +/- 10.53 micrometer) or group 2 (8.71 +/- 5.99 micrometer) (p = 0.001). The preoperative corneal topography of eyes observed in group 1 (0.19 +/- 0.13 mm) had shorter mean distances from maximum anterior elevation to pupil center than eyes in group 2 (0.47 +/- 0.23 mm) (p = 0.018). BCVA (log MAR) improved from 0.68 +/- 0.78 to 0.57 +/- 0.81 (p = 0.115) 12 months after CXL in group 1 and decreased from 0.51 +/- 0.34 to 0.56 +/- 0.38 (p = 0.109) 12 months after CXL in group 2. The maximum keratometry decreased from 63.01 +/- 19.07D to 58.95 +/- 16.32D (p = 0.017) in group 1 and increased from 60.70 +/- 9.46D to 61.29 +/- 7.51D (p = 0.674) in group 2. CONCLUSIONS: Clinical and optical effects improved postoperatively in group 1, and were stabilized in group 2. The preoperative distance from maximum anterior elevation to pupil center and the anterior elevation changes after CXL were factors in predicting the CXL outcome.
Key Words: Anterior elevation changes;Corneal crosslinking;Keratoconus


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