J Korean Ophthalmol Soc > Volume 54(2); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(2):289-295.
DOI: https://doi.org/10.3341/jkos.2013.54.2.289    Published online February 28, 2013.
Age-Related Differences of Spectral-Domain Optical Coherence Tomography Data in Koreans.
Ji Young Suh, Hong Ryung Seo, Sae Heun Rho
Department of Ophthalmology, Dong-A University College of Medicine, Busan, Korea. shrho@donga.ac.kr
한국인의 스펙트럼영역빛간섭단층촬영 변수의 나이에 따른 차이
Department of Ophthalmology, Dong-A University College of Medicine, Busan, Korea
We evaluated the thickness of RNFL and optic nerve head parameters with age in normal eyes using Spectral-Domain Optical Coherence Tomography (SD-OCT). METHODS: A total of 128 normal Korean volunteers in different age groups were recruited (age range, 20-70 years). RESULTS: A significant negative correlation in average RNFL thickness with increasing age was found. The inferior areas (130.31 +/- 3.33 micrometer) were significantly thicker than other areas (superior area 119.05 +/- 2.12 micrometer, nasal area 71.80 +/- 0.57 micrometer, temporal area 77.72 +/- 0.16 micrometer). The average C/D ratios (mean 0.38 +/- 0.14) and vertical C/D ratios (mean 0.35 +/- 0.11) both showed significant increases with age, and the vertical C/D ratio correlation coefficient was higher (average C/D ratio r = 0.249, vertical C/D ratio r = 0.537). However, rim area, disc area, and cup volume were not correlated with age. CONCLUSIONS: From these findings, we conclude that, in normal Koreans, the mean RNFL thickness decreases and the C/D ratio increases with age, with the increase in the vertical C/D ratio being greater.
Key Words: Optic disc parameter;Retinal nerve fiber layer thickness;Spectral-domain optical coherence tomography

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