| Effects of Cyclosporine 0.05% Ophthalmic Emulsion to Improve Reduction of Tear Production after Cataract Surgery. |
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Ae Ri Yoo, Hyung Bin Hwang, Hyun Kyung Kim, Sung Kun Chung |
1Department of Ophthalmology and Visual Science, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. eyedoc@catholic.ac.kr
2Department of Ophthalmology and Visual Science, St. Vincent's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. |
| 싸이클로스포린 0.05% 점안액이 백내장 수술 후 발생하는 눈물분비 감소에 미치는 영향 |
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유애리1⋅황형빈1⋅김현경2⋅정성근1 |
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Department of Ophthalmology and Visual Science, St. Mary’s Hospital1, St. Vincent’s Hospital2, The Catholic University of Korea College of Medicine, Seoul, Korea |
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| Abstract |
PURPOSE
To evaluate the efficacy of cyclosporine 0.05% in reduced tear production sign and dry eye symptoms after cataract surgery. METHODS: This hospital-based prospective randomized trial included 43 patients of 83 eyes who underwent phacoemulsification. Tear break-up time, Schirmer's test, corneal and conjunctival stain, and ocular surface disease index were performed for all patients at preoperative 1 day, and 1 day, 1 week, 1 month, and 2 months postoperatively. Group 1 received carboxymethylcellulose 0.5%, group 2 received twice-daily cyclosporine 0.05%, and group 3 did not receive any additional eye drops. RESULTS: There was no statistically significant difference between the 3 groups in outcome measures. Two months after cataract surgery, the cyclosporine group showed improved tear break-up time, Schirmer's test I, and corneal and conjunctival staining. CONCLUSIONS: Cyclosporine 0.05% therapy reduced dry eye signs and symptoms after cataract surgery. |
| Key Words:
Cataract surgery;Cyclosporine;Dry eye;Phacoemulsification |
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