Central Corneal Thickness and Corneal Endothelial Cells in Pseudoexfoliation Syndrome.

Chang, In Boem; Paik, Dong Won; Kim, Tai Jin; Ha, Hyo Shin; Park, Jung Hyun

doi:2013.54.7.1060

J Korean Ophthalmol Soc > Volume 54(7); 2013 > Article

Original Article

Journal of the Korean Ophthalmological Society 2013;54(7):1060-1065.
DOI: https://doi.org/10.3341/jkos.2013.54.7.1060 Published online July 15, 2013.

Central Corneal Thickness and Corneal Endothelial Cells in Pseudoexfoliation Syndrome.

In Boem Chang, Dong Won Paik, Tai Jin Kim, Hyo Shin Ha, Jung Hyun Park

¹Department of Ophthalmology, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea. hyuny@medimail.co.kr
²Department of Ophthalmology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

거짓비늘증후군의 중심각막두께 및 각막내피세포에 대한 분석

장인범¹⋅백동원²⋅김태진¹⋅하효신¹⋅박정현¹

Department of Ophthalmology, Seoul Paik Hospital, Inje University College of Medicine¹, Seoul, Korea Department of Ophthalmology, Sanggye Paik Hospital, Inje University College of Medicine², Seoul, Korea

Abstract

PURPOSE
To evaluate the central corneal thickness (CCT) and corneal endothelial cell density (ENDO) in pseudoexfoliation syndrome. METHODS: Medical records of patients who underwent a preoperative examination for cataract surgery and an examination for glaucoma were retrospectively reviewed. The present study included 44 patients (59 eyes) and age- and sex-matched controls. The total pseudoexfoliation patients divided into 2 groups, such as pseudoexfoliation syndrome (28 eyes) and pseudoexfoliative glaucoma (21 eyes) .The intraocular pressure (IOP), CCT, ENDO, corneal curvature (CC) and axial length (AL) were measured. RESULTS: The total pseudoexfoliation group showed significantly higher IOP (p = 0.001), thinner CCT (p = 0.003) and lower ENDO (p = 0.037). The pseudoexfoliation syndrome group showed significantly thinner CCT (p = 0.010) and lower EDNO (p = 0.041), but no significant difference in IOP (p = 0.941). There was no significant difference in CCT (p = 0.060) and ENDO (p = 0.171) between the pseudoexfoliative glaucoma group and controls, but the pseudoexfolliative glaucoma group showed significantly higher IOP (p < 0.001). CONCLUSIONS: The pseudoexfoliation group showed thinner CCT which should be taken into consideration when evaluating IOP with the applanation tonometer and diagnosing glaucoma, especially in pseudoexfoliation syndrome patients.

Key Words: Central corneal thickness;Corneal curvature;Corneal endothelial cell density;Pseudoexfoliation syndrome