J Korean Ophthalmol Soc > Volume 54(8); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(8):1287-1292.
DOI: https://doi.org/10.3341/jkos.2013.54.8.1287    Published online August 15, 2013.
Rapidly Progressing Foveal Atrophy with Tuberculous Serpiginous-Like Choroiditis Despite Combined Anti-Tuberculosis and Steroid Treatment.
Jin Young Lee, Kun Wook Kang, Jae Pil Shin, In Taek Kim, Dong Ho Park
Department of Ophthalmology, Kyungpook National University School of Medicine, Daegu, Korea. sarasate2222@gmail.com
결핵 뱀모양 맥락막염 환자에서 항결핵제와 스테로이드 치료 후에도 급격히 진행된 중심와 위축
이진영⋅강건욱⋅신재필⋅김인택⋅박동호
Department of Ophthalmology, Kyungpook National University School of Medicine, Daegu, Korea
Abstract
PURPOSE
To report a case of rapidly progressing foveal atrophy with tuberculous serpiginous-like choroiditis. CASE SUMMARY: A 54-year-old female patient had decreased vision of hand motions (os) for 3 days. Fundus examination showed optic disc swelling and yellowish chorioretinal lesions in the posterior pole (os). Optical coherence tomography (OCT) showed intraretinal edema and subretinal fluid in the left macula. Routine laboratory tests, serologic tests, and magnetic resonance imaging results were normal except for erythrocyte sedimentation rate (28 mm/hr). Fluorescein angiography showed the chorioretinal lesions appeared to be early hypofluorescence followed by late hyperfluorescence. Indocyanine green angiography showed hypofluorescence during early and late phases and the result of interferon-gamma release assay was positive. Under diagnosis of tuberculous serpiginous-like choroiditis, anti-tuberculous therapy combined with systemic corticosteroid was started. Despite decreased optic disc swelling, OCT showed a rapid progression of foveal atrophy within 2 weeks. Twelve weeks later, visual acuity was finger count at 10 cm. Six months later, best-corrected visual acuity and foveal atrophy were no interval change. CONCLUSIONS: Tuberculous serpiginous-like choroiditis with foveal involvement can show rapidly progressive foveal atrophy and poor visual prognosis.
Key Words: Anti-tuberculous therapy;Foveal atrophy;Indocyanine green angiography;Interferon-gamma release assay;Tuberculous serpiginous-like choroiditis
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