| A Case of Periorbital Infantile Capillary Hemangioma Treated With Propranolol. |
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Eun Kyoung Lee, Ho Kyung Choung, Nam Ju Kim, Min Joung Lee, Bo Sang Kwon, Sang In Khwarg |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. hokyung@medimail.co.kr
2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea.
4Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
5Department of Pediatrics, Seoul National University Boramae Hospital, Seoul, Korea. |
| 프로프라놀롤 치료를 시행한 유아모세혈관종 1예 |
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이은경1,2ㆍ정호경1,3ㆍ김남주1,4ㆍ이민정1,2ㆍ권보상5ㆍ곽상인1,2 |
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Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute2, Seoul, Korea Department of Ophthalmology, Seoul National University Boramae Hospital3, Seoul, Korea Department of Ophthalmology, Seoul National University Bundang Hospital4, Seongnam, Korea Department of Pediatrics, Seoul National University Boramae Hospital5, Seoul, Korea |
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| Abstract |
PURPOSE
To report a case of periorbital infantile capillary hemangioma treated with propranolol. CASE SUMMARY: A 6-month-old girl visited our clinic for a mass on the right upper eyelid, which had been present since birth. A dome-shaped, red-purple colored mass occupying almost the entire right upper eyelid was observed, and overlying branch-shaped telangiectases were also detected. The visual axis of the right eye was partially obscured, due to the ptotic eyelid, and her ability to fix and follow was poor in the right eye. The patient was diagnosed with infantile capillary hemagioma. Because amblyopia in her right eye was suspected, treatment with propranolol was initiated. After 2.5 months of propranolol treatment, the hemangioma decreased in size and volume dramatically, changed from red-purple to light red color, and softened. The ptosis of the right upper eyelid improved, as well as the ability of the right eye to fix and follow. No significant adverse effects (e.g. hypotension, bradycardia, hypoglycemia, bronchospasm, or elevated liver enzymes) were observed, except transient QTc prolongation during cotreatment with ibuprofen, due to an upper respiratory infection. CONCLUSIONS: Propranolol should be considered as a treatment option for periorbital infantile capillary hemangioma. Further clinical studies are required to establish the optimal guidelines and long-term outcome. |
| Key Words:
Hemangioma of infancy;Infantile capillary hemangioma;Periorbital hemangioma;Propranolol |
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