A Case of Muir-Torre Syndrome.

Bae, Kunho; Kim, Yoon Duck; Woo, Kyung In

doi:2011.52.3.355

J Korean Ophthalmol Soc > Volume 52(3); 2011 > Article

Case Report

Journal of the Korean Ophthalmological Society 2011;52(3):355-358.
DOI: https://doi.org/10.3341/jkos.2011.52.3.355 Published online March 15, 2011.

A Case of Muir-Torre Syndrome.

Kunho Bae, Yoon Duck Kim, Kyung In Woo

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eyeminded@hanmail.net

성인의 눈꺼풀에 발생한 Muir-Torre 증후군 1예

배건호⋅김윤덕⋅우경인

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

PURPOSE
To present a rare case of Muir-Torre syndrome characterized by the association of sebaceous skin tumors and systemic malignancies. CASE SUMMARY: A 65-year-old female visited our clinic with an irregular nodular mass of the right lower eyelid, which developed 1 year earlier. An excisional biopsy and lower lid reconstruction with Tenzel's semicircular rotational flap was performed under local anesthesia. Histopathologic examination showed well-differentiated sebaceous cells, consistent with sebaceous adenoma. The patient had undergone total abdominal hysterectomy and lower anterior resection due to endometrial cancer and sigmoid colon cancer 5 years before, and nephroureterectomy due to papillary urothelial carcinoma 3 years before. Based on the history of systemic malignancy and sebaceous skin cancer, a diagnosis of Muir-Torre syndrome was made. CONCLUSIONS: When a sebaceous gland tumor of the eyelids is detected, Muir-Torre syndrome should be included in the differential diagnosis, and systemic work-up for the internal malignancy must be performed.

Key Words: Eyelid tumor;Muir-Torre syndrome;Sebaceous;Systemic malignancy