J Korean Ophthalmol Soc > Volume 52(5); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(5):544-549.
DOI: https://doi.org/10.3341/jkos.2011.52.5.544    Published online May 15, 2011.
The Change in Corneal Endothelial Cell Density after Pars Plana Vitrectomy.
Ja Young Lee, Mi Ri Rhee, Kyung Seek Choi, Sung Jin Lee
1Department of Ophthalmology, Soonchunhyang University College of Medicine, Seoul, Korea. wismile@unitel.co.kr
2Myeong Eye Clinic, Seoul, Korea.
유리체절제술 시행 후 각막내피세포밀도의 변화
이자영1⋅이미리2⋅최경식1⋅이성진1
Department of Ophthalmology, Soonchunhyang University College of Medicine1, Seoul, Korea Myeong Eye Clinic2, Seoul, Korea
Abstract
PURPOSE
To assess the effect of pars plana vitrectomy and gas tamponade on corneal endothelial cell density. METHODS: The corneal endothelial cell density in 145 eyes that underwent pars plana vitrectomy was examined with a noncontact specular microscope 3 months pre- and post-operation. The subjects were divided as follows: Group 1 (32 eyes) underwent pars plana vitrectomy, group 2 (26 eyes) underwent pars plana vitrectomy combined with gas tamponade, group 3 (34 eyes) underwent pars plana vitrectomy combined with phacoemulsification and group 4 (48 eyes) underwent pars plana vitrectomy combined with phacoemulsification and gas tamponade. The changes in corneal endothelial cell density between groups was compared. RESULTS: The mean endothelial cell loss was more significant in group 2 than in group 1 (p = 0.012), and there was no difference between groups 3 and 4 (p = 0.063). However, after excluding 6 eyes that had blood in the center of the corneal endothelium as a result of being in the prone position following gas tamponade, the mean endothelial cell loss in group 2 was not less than in group 1. In eyes with blood in the corneal endothelium, endothelial cell loss significantly increased (p < 0.001). CONCLUSIONS: The results of this study suggest that ophthalmic surgeons should attempt to carefully control bleeding and sufficiently irrigate the vitreous during pars plana vitrectomy combined with gas tamponade.
Key Words: Corneal endothelial cell loss;Gas tamponade;Phacoemulsification;Vitrectomy


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