J Korean Ophthalmol Soc > Volume 52(6); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(6):679-689.
DOI: https://doi.org/10.3341/jkos.2011.52.6.679    Published online June 15, 2011.
Long-term Clinical Outcomes of Femtosecond LASER-Assisted Descemet's Stripping Endothelial Keratoplasty.
Byung Gil Moon, Jae Hyung Kim, Joo Eun Lee, Myoung Joon Kim, Jae Yong Kim, Hungwon Tchah
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. hwtchah@amc.seoul.kr
펨토초 레이저를 이용한 데스메막박리 각막내피층판 이식술의 장기 임상경과
문병길⋅김재형⋅이주은⋅김명준⋅김재용⋅차흥원
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Abstract
PURPOSE
To evaluate the long-term clinical outcomes of femtosecond LASER-assisted Descemet's stripping endothelial keratoplasty (DSEK). METHODS: The clinical results of endothelial keratopathy from 11 consecutive patients who were followed up for at least 12 months after femtosecond LASER-assisted DSEK were retrospectively analyzed. The best corrected visual acuities (BCVA), manifest refractions, intraocular pressures, and perioperative complications were evaluated preoperatively and up to 24 months after the femtosecond LASER-assisted DSEK. RESULTS: The average follow-up period was 18 months. Postoperative visual acuity had significantly improved from 1.26 (logMAR) to 0.80 (logMAR) at 3 months (p < 0.05) and this change was maintained during postoperative follow-up. All eyes underwent successful transplantation and the donor discs were well-attached. The mean endothelial cell density continued to decrease during the follow-up period. The donor-recipient stromal interface was the area where varying degree of haziness and birefringent particles were found. CONCLUSIONS: The femtosecond LASER-assisted DSEK was effective in creating an endothelial donor disc which resulted in rapid visual recovery and low surgically-induced astigmatism. However, the operation caused rapid decrease in endothelial cell density which requires continuing further consideration by the physician.
Key Words: Anterior segment optical coherent tomography;Confocal microscopy;Femtosecond LASER-assisted Descetmet's stripping endothelial keratoplasty


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