| Risk Factors for Dry Eye in Thyroid-Associated Ophthalmopathy. |
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Jae Ryun Kim, Hye Bin Yim, Sung Kun Chung |
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Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. eyedoc@catholic.ac.kr |
| 갑상샘안병증에서 건성안에 영향을 미치는 인자 |
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김재련⋅임혜빈⋅정성근 |
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Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea |
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| Abstract |
PURPOSE
To investigate the risk factors for dry eye in thyroid-associated ophthalmopathy patients. METHODS: The present retrospective study was conducted on 78 eyes in 39 patients diagnosed with thyroid-associated ophthalmopathy. The risk factors for dry eye in thyroid-associated ophthalmopathy patients were examined by analyzing data including tear break-up time, Schirmer's test, age, gender, thyroid function status, palpebral fissure width, lagophthalmos, eyelid retraction, and exophthalmos through multiple logistic regression analysis. RESULTS: The risk factors for dry eye disease were palpebral fissure width (OR = 3.422, p = 0.022) and lagophthalmos (OR = 13.068, p = 0.049). Age, gender, thyroid hormone status, eyelid retraction and exophthalmos did not show significant association with dry eye in multiple logistic regression analysis. The only risk factor for tear film break-up time less than 10 seconds was palpebral fissure width (OR = 2.787, p = 0.045), and none of the risk factors for Schirmer's test less than 10 mm at 5 minutes were statistically significant. CONCLUSIONS: Risk factors for dry eye in thyroid ophthalmopathy patients were palpebral fissure width and lagophthalmos. |
| Key Words:
Dry eye syndrome;Risk factors;Thyroid-associated ophthalmopathy |
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