J Korean Ophthalmol Soc > Volume 52(9); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(9):1030-1038.
DOI: https://doi.org/10.3341/jkos.2011.52.9.1030    Published online September 15, 2011.
Changes in Clinical Manifestations of Dry Eye Syndrome after Cataract Surgery and the Affecting Factors.
Young Rae Roh, Sang Mok Lee, Young Keun Han, Mee Kum Kim, Won Ryang Wee, Jin Hak Lee
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. lsm10003@chollian.net
2Department of Ophthalmology, The Armed Forces Capital Hospital, Seongnam, Korea.
3Department of Ophthalmology, Seoul National University Boramae Medical Center, Seoul, Korea.
4Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
5Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
백내장 수술 후 발생하는 안구건조증의 임상양상 및 영향을 미치는 요인에 대한 분석
노영래1⋅이상목1,2,3⋅한영근1,3⋅김미금1,4⋅위원량1,4⋅이진학1,4,5
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Department of Ophthalmology, The Armed Forces Capital Hospital2, Seongnam, Korea Department of Ophthalmology, Seoul National University Boramae Medical Center3, Seoul, Korea Department of Ophthalmology, Seoul National University Hospital4, Seoul, Korea Department of Ophthalmology, Seoul National University Bundang Hospital5, Seongnam, Korea
Abstract
PURPOSE
To evaluate the changes in the clinical signs and symptoms of dry eye syndrome before and after cataract surgery according to the main incision location and the type of artificial tears. METHODS: Twenty-four eyes of 17 patients who underwent phacoemulsification and posterior chamber lens insertion from May 2009 to July 2009 were enrolled in the present study prospectively. The main incision location (temporal or superior incision) was determined according to the axis of astigmatism and the postoperative artificial tears (sodium hyaluronate with or without preservatives) were determined randomly. The tear film break-up time (TF-BUT), Schirmer test, esthesiometer, corneal surface grading with Oxford system and ocular surface disease index (OSDI) questionnaire before and 1, 2 and 6 months after surgery were evaluated. The corneal nerve was also analyzed using corneal confocal microscopy (Confoscan 4, Nidek, Italy) before, and 1 and 6 months after surgery. RESULTS: The TF-BUT was significantly longer (p = 0.010) and the OSDI score was significantly lower (p = 0.007) in the patient group with preservative-free sodium hyaluronate than the group with sodium hyaluronate containing preservatives at 6 months after cataract surgery. There were no statistically significant differences according to the main incision location in the sodium hyaluronate without preservatives group. CONCLUSIONS: Symptoms and several signs of dry eye syndrome triggered by cataract surgery decreased with preservative- free artificial tears compared to tears with preservatives.
Key Words: Artificial tears;Cataract surgery;Corneal nerve;Dry eye syndrome;Preservatives


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