J Korean Ophthalmol Soc > Volume 52(9); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(9):1083-1088.
DOI: https://doi.org/10.3341/jkos.2011.52.9.1083    Published online September 15, 2011.
Clinical Features and the Effect of High-Dose Steroid Therapy in Korean Optic Neuritis Patients.
Dong Min Cha, Seong Joon Kim, Jeong Hun Kim, Ho Kyung Choung, Young Suk Yu
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. ophjun@gmail.com
2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
3Department of Ophthalmology, Seoul Metropolitan Boramae Hospital, Seoul, Korea.
한국인 시신경염 환자의 임상 양상 및 고용량 스테로이드 치료 효과
차동민1,2⋅김성준1,2⋅김정훈1,2⋅정호경1,3⋅유영석1,2
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute2, Seoul, Korea Department of Ophthalmology, Seoul Metropolitan Boramae Hospital3, Seoul, Korea
Abstract
PURPOSE
To investigate the clinical manifestation and response to high-dose steroid therapy in Korean optic neuritis patients. METHODS: We retrospectively reviewed the medical records of 13 patients diagnosed with optic neuritis who were treated with high-dose steroid and who were followed-up for more than three months in Seoul National University Hospital between January 2005 and December 2008. RESULTS: Pain on extraocular movement (EOM) and disc swelling were observed in 61% (8/13) patients diagnosed with optic neuritis. Visual acuity (VA) improved to more than 20/40 in 77% (10/13) of patients after high-dose steroid therapy. The patients who resolved within one month recovered VA a mean of 18 days after onset. The recovery period had nothing to do with the initial time of high-dose steroid therapy. CONCLUSIONS: Pain on EOM was less frequently observed and disc swelling was more frequent in Korean patients than have been reported in Caucacian patients. The recovery period of optic neuritis was not influenced by the initial time of high-dose steroid therapy.
Key Words: Methylprednisolone;Optic neuritis;Pulse steroid therapy


ABOUT
BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos08@ophthalmology.org                

Copyright © 2021 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next